Cellular Dynamics and Pattern Formation in Vertebrate Development The Francis Crick Institute in United Kingdom

PhD opportunity: How the embryo gets its shape at the Medical Research Council (Cambridge), Laboratory of Molecular Biology, with Dr K McDole. This project focuses on cell biology , developmental biology , and molecular biology , asking how complex 3D structures arise from initially homogeneous cell populations during early mammalian development. The lab studies how tissues fold, tubes involute, organs form, and how physical forces and changing mechanical environments influence cell behavior, ge...

PhD opportunity: Epithelial Cell Fate and Plasticity at the University of Cambridge , hosted by the Cambridge Stem Cell Institute and led by Dr Maria P. Alcolea . This project sits at the intersection of cell biology , developmental biology , and cancer biology . The Alcolea Group studies how epithelial progenitor cells behave in the mouse oesophagus and how squamous epithelial cell fate changes during homeostasis, injury, and preneoplastic mutation. The research aims to understand mutant clonal...

PhD opportunity at the University of Dundee on how cell size controls cell fate during asymmetric cell division in the developing nervous system. This project sits in the Faculty of Life Sciences and uses Drosophila neural stem cells to investigate cell fate specification , asymmetric cell division , and the molecular mechanisms that drive unequal segregation of fate determinants. The work combines genetics , chemical genetics , CRISPR , confocal laser scanning microscopy , image analysis , and ...

PhD opportunity in Haematological Malignancies and Haematopoietic Stem Cell Biology at the University of Cambridge , Cambridge Stem Cell Institute, with Dr Adam Wilkinson and the Wilkinson Group. The project focuses on haematopoietic stem cells (HSCs) , blood cancers , cell biology , and developmental biology . Research themes include the molecular regulation of HSC self-renewal and lineage commitment, how HSC dysfunction can initiate blood cancer, and the development of novel HSC-based therapie...

PhD opportunity at the University of East Anglia in Norwich, United Kingdom, focused on single-cell multi-omics , enhancer biology , and the developmental control of blood and cardiovascular fate . The project investigates how enhancer activity changes as blood, endothelial, and cardiac lineages emerge in the chick embryo. You will combine single-cell RNA-sequencing and ATAC-sequencing to reconstruct gene-regulatory networks, identify candidate enhancers, and study how hematoendothelial progenit...