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Aurélie Carlier

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Marie Skłodowska-Curie PhD Candidate in Modelling Bone Healing and Remodelling Maastricht University in Netherlands

Degree Level

PhD

Field of study

Computer Science

Funding

Funded doctoral research position under the MSCA Doctoral Network framework, including mobility and, where eligible, family allowances; Dutch employment contract with gross monthly salary of €3,204–€4,051 plus holiday allowance and year-end bonus.

Deadline

Jan 31, 2027

Country flag

Country

Netherlands

University

Maastricht University

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Keywords

Computer Science
Biomedical Engineering
Mechanical Engineering
Materials Science
Biology
Mathematics
Systems Biology
Multiscale Modeling
Kidney Disease
Fracture
Bioinformatic
Physics

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About this position

This PhD project is part of EDI-MSK, a European Marie Skłodowska-Curie Actions Doctoral Network focused on making musculoskeletal modelling more inclusive, personalised and clinically relevant. The project addresses an important challenge in musculoskeletal health: understanding how diversity, bias, and biological variation should be reflected in next-generation models of bone and related tissues.

The specific doctoral project (DC6) aims to develop multiscale models of how chronic kidney disease affects bone healing and remodelling. You will work on identifying the mechanisms by which uremic toxins influence bone regeneration through network models of cells and signalling pathways, then connect these biological effects with biomechanical models of healing and remodelling. The final goal is to build computational tools that can predict differences in fracture healing under realistic lower-limb conditions for patients with chronic kidney disease.

The project sits within a large interdisciplinary European consortium of 20 organisations across 10 countries, bringing together expertise in biomedical science, engineering, imaging, simulation, experimental work, and clinical research. As a doctoral candidate, you will join a cohort of researchers working across academia and industry, with collaboration spanning Maastricht University, other European universities, and the Society for In Silico Medicine.

At Maastricht University, the project is based in the Maastricht Centre for Systems Biology and Bioinformatics (MaCSBio). The centre is described as a research environment dedicated to understanding, simulating, and manipulating biological systems using advanced mathematical and computational methods, with current themes including systems biomedicine and computational neuroscience. You will work as part of a multidisciplinary team of modelling and simulation experts and musculoskeletal researchers, and you will also have supervision involvement from the University of Padua.

The role is strongly research-oriented and combines computational modelling, simulation, and interdisciplinary collaboration. It offers access to international training, advanced infrastructure, and a network designed to develop future leaders in musculoskeletal health research.

Funding details

Funded doctoral research position under the MSCA Doctoral Network framework, including mobility and, where eligible, family allowances; Dutch employment contract with gross monthly salary of €3,204–€4,051 plus holiday allowance and year-end bonus.

What's required

Applicants must have a Master’s degree in Biomedical Engineering or equivalent. They should have research experience or a strong interest in bone healing, modelling and simulation, and co-morbidities, plus flexibility to travel throughout Europe. Demonstrable training in mathematical or computational modelling of biological or physical systems is required, gained through coursework, a thesis, or a research project. Applicants should have experience with at least one scientific programming language such as Python, MATLAB, Julia, or C/C++. The research will be conducted in English, so proficiency above C1 level according to CEFR is required. Applicants must not yet have been awarded a doctorate degree, and must not have resided or carried out their main activity in the Netherlands for more than 12 months in the three years immediately prior to recruitment.

How to apply

Apply via the AcademicTransfer application link. Contact Aurélie Carlier for role information if needed and submit your application before the deadline. Interviews are expected in March-April 2027.

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Professors

Prof. at Maastricht University

University Name
Country flag

Netherlands

Research Interests

Bioinformatic

Kidney Disease

Multiscale Modeling

Biomedical Engineering

Biology

Prof. at Maastricht University

University Name
Country flag

Netherlands

Research Interests

Systems Biology

Biology

Mathematics

Materials Science

Mechanical Engineering

Prof. at Maastricht University

University Name
Country flag

Netherlands

Research Interests

Systems Biology

Bioinformatic

Mathematics

Biology

Computer Science