University of Exeter
1 year ago
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Medical Mycology University of Exeter in United Kingdom
Degree Level
Postdoc
Field of study
Biology
Funding
not provided
Deadline
Aug 31, 2028
Country
United Kingdom
University
University of Exeter
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About this position
This postdoctoral research associate position is based at the MRC Centre for Medical Mycology (MRC CMM) at the University of Exeter and is part of a newly funded five-year antifungal drug discovery programme. The programme is a collaboration between MRC CMM, the Dundee Drug Discovery Unit (DDU), and GSK Global Health Medicines R&D, forming a multidisciplinary team that covers all aspects of drug discovery up to candidate selection. The successful candidate will focus on two main areas: designing and constructing new bioluminescent and other reporter strains of human fungal pathogens to support the development of murine infection models for antifungal efficacy testing and in vitro screens; and contributing to the development, optimisation, and implementation of an automated workflow to determine drug susceptibility and resistance liabilities of novel antifungal drugs across a wide range of fungal pathogens.
This includes both in vitro and in vivo analyses, as well as supporting cross-profiling of hit and lead compounds against panels of human fungal pathogens. The role offers opportunities for career development, including continuing education, conference attendance, scientific publishing, and funding application development. Applicants should have experience culturing micro-organisms at containment level 2, measuring microbial growth, genetic engineering of pathogenic fungi (including Candida, Cryptococcus, and Aspergillus), and experience with murine infection models.
The University of Exeter is a member of the Russell Group and is highly ranked globally, offering a supportive and inclusive environment. The position is available immediately and is fixed-term until 31 August 2028. For further information, candidates are encouraged to contact Programme Lead Elaine Bignell by email.
What's required
Applicants must have experience culturing micro-organisms (bacteria or yeast/fungi) at containment level 2, measuring microbial growth using optical density or other methods, and performing genetic engineering of pathogenic fungi including Candida, Cryptococcus, and Aspergillus species. Experience with murine infection models is also required. Additional requirements and person specifications are available on the university's website via the 'Apply' button.
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ApplyKite TwinLearns as you applyMake your next move.
Prepare your application
Review drafts and confirm requirements with the university.