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University of Cambridge

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PhD in Genetic Conditions, Splice Variants, and Neurodevelopmental Diagnostics at University of Cambridge University of Cambridge in United Kingdom

Degree Level

PhD

Field of study

Computer Science

Funding

Competition-funded PhD project. Funding is available for academic year October 2027/28. Gates US applications (round 1) close 2026-10-14. Cambridge Trust and Gates Cambridge (round 2) deadline is 2026-12-08 to be eligible for funding. Funding is not available for Lent or Easter 2027 places because the funding deadline has passed; other funding would be needed for those starts.

Deadline

Dec 8, 2026

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Country

United Kingdom

University

University of Cambridge

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Keywords

Computer Science
Biology
Neuropsychology
Medical Science
Neurodevelopmental Disorders
Genetic
Splicing
ML

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About this position

PhD opportunity at the University of Cambridge in the Department of Clinical Neurosciences with Dr Elizabeth Radford.

This project focuses on genetic conditions, splice variants, deep intronic variants, and the diagnosis of rare monogenic and neurodevelopmental disorders. The research aims to improve how clinicians interpret non-coding variation in whole-genome sequencing data, especially variants that alter splicing and remain difficult to predict with current methods.

Students will work on scalable mutagenesis and functional genomics approaches such as prime editing and saturation genome editing, alongside cellular screens and machine learning methods. The project also explores therapeutic applications, including poison exon design and antisense oligonucleotides (ASOs), making it highly relevant to translational genomics and precision medicine.

Research themes: splicing regulation, cis-regulatory elements, genomic context, variant interpretation, rare disease diagnostics, therapeutic genome engineering, and computational prediction of splice-modulating variants.

Funding: competition-funded PhD project. Funding deadlines mentioned include Gates US round 1 (2026-10-14) and Cambridge Trust / Gates Cambridge round 2 (2026-12-08). The post notes that funding is not available for Lent or Easter 2027 starts unless other funding is secured.

Eligibility: PhD only; students worldwide may apply. The post does not list detailed academic prerequisites, but the topic suits applicants with interests in genetics, neuroscience, molecular biology, genomics, and computational biology.

How to apply: Register interest via the FindAPhD listing and follow the Cambridge application process. Make sure to indicate every funding scheme you are eligible for before the relevant deadlines.

Funding details

Competition-funded PhD project. Funding is available for academic year October 2027/28. Gates US applications (round 1) close 2026-10-14. Cambridge Trust and Gates Cambridge (round 2) deadline is 2026-12-08 to be eligible for funding. Funding is not available for Lent or Easter 2027 places because the funding deadline has passed; other funding would be needed for those starts.

What's required

PhD only. The project is aimed at students worldwide. The post does not specify prior degree class, language scores, or other formal entry requirements, but applicants should be prepared for research in genomics, splicing, cellular screening, and computational analysis.

How to apply

Register your interest through the FindAPhD page and submit your application to Cambridge while indicating all funding schemes you are eligible for. Check the Gates website and Cambridge postgraduate funding search for the relevant funding rounds and deadlines.

More information can be found here

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