PhD in Machine Learning Guided Sustainable Automated Synthesis and Target-Based Screening of Metal-Based Antibiotics University of York in United Kingdom

Funded PhD project at the University of Bristol in the School of Biochemistry and Biomedical Sciences, focused on β-lactamase-mediated antibiotic resistance , biomolecular simulation , enzyme kinetics , and X-ray crystallography . The project investigates how class C β-lactamases break down cephalosporin antibiotics and how diazabicyclooctanone (DBO) inhibitors block these enzymes. The research combines computational chemistry, structural biology, molecular biology/biochemistry, and kinetic expe...

Fully funded PhD opportunity at the University of York in the Frei Lab , working in collaboration with the INEOS Oxford Institute for Antimicrobial Research . This interdisciplinary studentship sits within the EPSRC Centre for Doctoral Training in Chemical Synthesis for a Healthy Planet (CSHP CDT) and combines machine learning , automated synthesis , robotics , antibiotic discovery , and inorganic chemistry . The project focuses on developing metal-based antibiotics using sustainable high-throug...

PhD opportunity at Cardiff University in the Cardiff School of Pharmacy and Pharmaceutical Sciences on designer proteins for targeting biofilm matrix carbohydrates and combating bacterial infections and antimicrobial resistance . The project focuses on biofilms formed by major pathogens including Pseudomonas aeruginosa , Staphylococcus aureus , and Streptococcus mutans . The research aims to design novel protein carbohydrate-binding domains that can recognize biofilm extracellular polysaccharide...

Postdoctoral Research Assistant opportunity in chemical biology and medicinal chemistry at the University of Oxford , Department of Pharmacology, working with the Lanyon-Hogg group . The project focuses on developing novel molecules to combat drug-resistant infections and address antimicrobial resistance . Research activities include design, synthesis, and biological testing/target profiling of small molecule inhibitors and chemical probes, along with data analysis, publication writing, presenta...

Fully funded PhD opportunity in medicinal chemistry at Newcastle University , within the Newcastle Medicinal Chemistry Group. The project focuses on high-throughput chemistry and direct-to-biology screening , with supervision involving Mike Waring and Hannah Stewart, and collaboration with Charles A. and Liz McFaddin at Eli Lilly and Company . This is a research-focused doctoral opening for candidates interested in drug discovery, screening workflows, and modern medicinal chemistry approaches. T...