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Andrew Lin

11 months ago

PhD in Neuronal Compensation for Natural Circuit Perturbations (BBSRC Yorkshire Bioscience DLA Programme) University of Sheffield in United Kingdom

Degree Level

PhD

Field of study

Neuroscience

Funding

Funded PhD Project (Students Worldwide)

Deadline

Expired

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Country

United Kingdom

University

University of Sheffield

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Keywords

Neuroscience
Biology
Developmental Biology
Electrophysiology
Chemical Biology
Calcium Signaling
Behavioral Neuroscience
Quantitative Imaging
Homeostasis
Genetic
Synaptic Biology
Drosophila Melanogaster
Computational Modelling

About this position

This fully funded PhD project, part of the BBSRC Yorkshire Bioscience Doctoral Training Partnership (YBDTP), investigates how neural circuits in the brain compensate for natural environmental changes, focusing on homeostatic plasticity. The research addresses a fundamental question in neuroscience: how do brains maintain stable function despite natural perturbations such as temperature changes? Using the fruit fly (Drosophila) as a model, the project explores how developmental temperature affects brain wiring and synaptic connections, and how the brain compensates to maintain consistent neural activity.

The research will employ advanced techniques including electrophysiology, calcium imaging, genetic tagging, and computational modelling to test hypotheses about the roles of inhibitory circuits and intrinsic neuronal properties in maintaining neural stability. The successful candidate will receive interdisciplinary training in experimental and theoretical neuroscience, including live-brain recordings, molecular labelling, quantitative image analysis, and computational modelling.

The project is supervised by Dr Andrew Lin and Prof Mikko Juusola at the University of Sheffield's School of Biosciences, within a collaborative team with expertise in electrophysiology, in vivo imaging, Drosophila genetics, and computational neuroscience. The YBDTP offers a vibrant regional doctoral training programme, supporting researchers across multiple Yorkshire and Teesside universities. The studentship is open to UK, EU, and international students, with a competitive selection process and a limited number of full studentships for exceptional international applicants.

Funding includes a tax-free stipend at the UKRI rate (£20,780 for 2025/26), research costs, and tuition fees at the UK rate for four years. Applicants should have or expect at least an upper second-class honours degree in a relevant field (biological, chemical, or physical sciences, or mathematics), and demonstrate motivation to bridge experiments and theory in neuroscience.

The programme values diversity and encourages applications from underrepresented groups. The application deadline is 7 January 2026, with interviews in February 2025. For more information or to apply, visit the YBDTP website or contact the supervisors directly.

Funding details

Funded PhD Project (Students Worldwide)

What's required

Applicants must have, or expect to gain, at least an upper second-class honours degree or equivalent in a biological, chemical, or physical science, or mathematics. The programme welcomes candidates from neuroscience, biology, physics, or related quantitative fields. International students must meet the entry requirements for the host university and provide evidence of English language proficiency if English is not their first language. Only a limited number of full studentships are available for international applicants, awarded competitively. All applicants should demonstrate curiosity, creativity, and a drive to learn new skills.

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Professors

Dr at School of Biosciences

University Name
Country flag

United Kingdom

Research Interests

Behavioral Neuroscience

Chemical Biology

Computational Modelling

Electrophysiology

Neuroscience

Prof at School of Biosciences

University Name
Country flag

United Kingdom

Research Interests

Behavioral Neuroscience

Systems Neuroscience

Oculomotor Control

Swarm Intelligence

Super-resolution Microscopy