Publisher
source

The Francis Crick Institute

PhD in The Evolutionary Logic of Amniogenesis: lessons from stem cell models The Francis Crick Institute in United Kingdom

Degree Level

PhD

Field of study

Cell Biology

Funding

Funded PhD project. Successful applicants will receive a non-taxable annual stipend of £27,715 plus payment of university tuition fees. Students of all nationalities are eligible to apply.

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Country

United Kingdom

University

The Francis Crick Institute

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Keywords

Cell Biology
Molecular Biology
Evolutionary Biology
Biomedical Engineering
Biology
Stem Cell Biology
Tissue Engineering
Developmental Biology
Reproductive Biology
Quantitative Imaging

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About this position

PhD opportunity at The Francis Crick Institute in developmental biology, stem cell biology, and evolution.

This funded PhD project, titled The Evolutionary Logic of Amniogenesis - lessons from stem cell models, is with Dr Silvia Santos at the Francis Crick Institute in London, United Kingdom. The project investigates how the amnion forms across species, with a focus on comparing human development with mouse and chicken to understand the evolutionary and mechanistic logic of amniogenesis.

The research will use embryonic stem cells from three species and develop 3D stem cell-based models of the amnion. Planned work includes comparing signaling requirements for amnion specification, quantitatively characterizing morphogenesis using long-term light-sheet imaging, and identifying transcription factors that drive amniogenesis. The project sits at the intersection of cell biology, molecular biology, reproductive biology, tissue engineering, and quantitative developmental biology.

Training will include advanced methods such as single-cell technologies, OMICS, CRISPR, biosensors, screening and automation, and imaging of early development models. The lab emphasizes a collaborative and interdisciplinary environment.

Eligibility: applicants should have a degree in the Life Sciences or a background relevant to cell, developmental, or quantitative biology. Motivation to work with cutting-edge techniques and to contribute to a collegial, interdisciplinary team is important.

Funding: the studentship provides a non-taxable annual stipend of £27,715 plus university tuition fees. Students of all nationalities may apply.

Application: the listing includes a lab-specific question asking applicants either to discuss a memorable lecture/seminar/paper and why it mattered, or to explain what aspect of the lab's research they would like to explore and what perspective they would bring.

Funding details

Funded PhD project. Successful applicants will receive a non-taxable annual stipend of £27,715 plus payment of university tuition fees. Students of all nationalities are eligible to apply.

What's required

Applicants should have any degree in the Life Sciences or a background in relevant areas to cell biology, developmental biology, and quantitative biology. Strong motivation to work with state-of-the-art techniques including single-cell technologies, 3D organoid models, OMICS, and imaging is expected. The project suits candidates interested in interdisciplinary, highly collegial, and collaborative research.

How to apply

Read the project details and answer the lab-specific question in your application. Prepare a response to one of the two prompts about a memorable lecture/paper or your interest in the lab's research. Apply through the FindAPhD listing or the institution's application route if provided on the project page.

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