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University of Groningen

PhD Position in Chemical Synthesis of Complex Bacterial Glycans at University of Groningen University of Groningen in Netherlands

Degree Level

PhD

Field of study

Biochemistry

Funding

This is a fully funded 4-year PhD position. The salary ranges from €3,059 to €3,881 gross per month for full-time employment. Additional benefits include 232 vacation hours per year (based on a 38-hour workweek), end-of-year bonus of 8.3%, 8% holiday allowance, and extensive opportunities for personal and professional development. The contract is initially for one year, with renewal for three more years contingent on progress.

Deadline

Expired

Country flag

Country

Netherlands

University

University of Groningen

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Keywords

Biochemistry
Chemistry
Microbiology
Organic Chemistry
Biology
Gut Health
Chemical Synthesis
Chemical Biology
Glycobiology
Carbohydrate Chemistry

About this position

The University of Groningen is offering a fully funded 4-year PhD position in the Chemical Glycobiology group of Prof. Marthe Walvoort, within the Stratingh Institute for Chemistry. The research focuses on the chemical synthesis of complex bacterial glycans, specifically exopolysaccharides produced by bifidobacteria, which are associated with beneficial effects on human health such as immune modulation and gut health. The project aims to develop new chemical synthesis methods to produce a variety of bifidobacterial exopolysaccharides, including novel sugar-nucleotides and glycolipids, using a modular approach to obtain different lengths and complexities. The synthesized structures will be tested for their functional effects in intestinal model systems, contributing to the understanding of structure-activity relationships and laying the foundation for future antibacterial therapies.

The position is part of the NWO-Vidi project ‘Healthy sugars for a healthy gut’ and involves close collaboration with another PhD project on enzymatic production of EPS structures, promoting interdisciplinary research. The successful candidate will join a top-tier research group in a vibrant academic environment, with access to extensive personal and professional development opportunities. The Faculty of Science and Engineering at the University of Groningen is renowned for its interdisciplinary research and inclusive community, with over 7,000 students and 1,400 staff members from around the world.

Applicants should have an MSc degree in (synthetic) organic chemistry or equivalent, with a strong experimental background in synthetic organic (carbohydrate) chemistry. Research experience in carbohydrate chemistry is highly valued. Candidates must be highly motivated, able to work in international teams, and possess excellent communication skills. Proficiency in English is required. The position offers a competitive salary, generous vacation allowance, bonuses, and a supportive academic environment. The application deadline is December 2, 2025, and the preferred starting date is March 1, 2026 or later. For more information, contact Associate Professor Marthe Walvoort at [email protected].

To apply, submit a letter of motivation, CV with references, research experience description, and transcripts via the university’s application portal. The selection process includes interviews and assessment, with feedback provided within two weeks of the closing date.

Funding details

This is a fully funded 4-year PhD position. The salary ranges from €3,059 to €3,881 gross per month for full-time employment. Additional benefits include 232 vacation hours per year (based on a 38-hour workweek), end-of-year bonus of 8.3%, 8% holiday allowance, and extensive opportunities for personal and professional development. The contract is initially for one year, with renewal for three more years contingent on progress.

What's required

Applicants must hold an MSc degree in (synthetic) organic chemistry or an equivalent certification. A strong experimental background in synthetic organic (carbohydrate) chemistry is required. Research experience in carbohydrate chemistry is considered a strong asset. Candidates should demonstrate analytical and creative thinking, high motivation for academic research, ability to work in an international team, and excellent communicative and social skills. Fluent proficiency in English, both written and oral, is mandatory.

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Professors

Professor at University of Groningen

University Name
Country flag

Netherlands

Research Interests

Microbiology

Biochemistry

Gut Microbiota

Glycobiology

Mucosal Biology