PhD Position in Organic Chemistry and Chemical Biology for Antimicrobial Drug Discovery (France) Institut CARMeN-Caen in France

CNRS Research Director Anton Granzhan is recruiting for an 18-month postdoctoral position in bioorganic chemistry and chemical biology at LCBPT (CNRS – Université Paris Cité, Paris, France). The project builds on a recent discovery of small molecules that selectively bind DNA three-way junctions and show toxicity against certain cancer cells. The next stage is to design a new generation of macrocyclic TWJ ligands and heterobifunctional probes to investigate how these molecules act in cells. Suit...

This postdoctoral project sits at the interface of organic synthesis and chemical biology, with a clear biomedical orientation toward anticancer research. The recruited researcher will help develop polyazamacrocyclic compounds as ligands for non-canonical nucleic acid structures , especially DNA three-way junctions , and then functionalize these molecules for chemical-biology applications. The position involves hands-on organic synthesis and molecular characterization , together with participati...

Master 2 internship opportunity in the Pharmacy department of UFR3S at the University of Lille , France. The project focuses on accelerated virtual screening of the GPR35 receptor for inflammatory bowel disease , with an emphasis on identifying new selective GPR35 agonists, ideally biased toward the anti-inflammatory β-arrestin-2 pathway. The intern will work with Corentin Bedart in the In silico Lille research group (Inserm Unit U1286 INFINITE). Planned work includes: developing a complete deep...

George Washington University is advertising a Postdoctoral Associate position in the Chemistry Department focused on the design, synthesis, characterization, and evaluation of novel antibiotics and their prodrugs . The role is based at GW’s Foggy Bottom campus in Washington, D.C., United States , and is an on-campus, full-time appointment. The postdoctoral researcher will work closely with the PI, undergraduate and graduate students, and project team members to design and run specialized experim...

Post-doctoral Fellow in Organic Chemistry at Lund University , Sweden. This postdoctoral opening sits at the interface of organic chemistry and chemical biology , with a strong focus on targeted protein degradation in bacteria. The project develops a modular chemical platform for BacPROTACs as a new strategy against antimicrobial resistance (AMR), aiming to design bifunctional molecules that recruit bacterial proteolytic machinery such as the ClpC:ClpP system to selectively degrade essential pro...