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Thijs van Osch

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PhD Position in Radiology on Brain Clearance and Dementia Research Leids Universitair Medisch Centrum in Netherlands

Degree Level

PhD

Field of study

Physiology

Funding

Paid PhD position with salary of €3,217 to €4,077 gross per month on a full-time basis (scale PRO, CAO UMC), 4-year fixed-term appointment at LUMC.

Deadline

Nov 5, 2026

Country flag

Country

Netherlands

University

Universitair Medisch Centrum Utrecht

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Keywords

Physiology
Neurology
Radiology
Medical Imaging
Biology
Alzheimer's Disease
Neuropsychology
Magnetic Resonance Imaging
Near-infrared Spectroscopy
Cerebrospinal Fluid
Physics

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About this position

This PhD project at Leiden University Medical Center focuses on brain clearance: how the brain removes waste products and how disturbances in this process may contribute to dementia. The student will investigate cerebrospinal fluid dynamics and related mechanisms using innovative MRI techniques together with a wearable measurement device called the glymphometer, which is based on near-infrared spectroscopy and can be worn overnight.

The research combines technical development with clinical investigation in older adults with memory problems and patients with hypertension. The PhD candidate will be involved in study design, participant inclusion and supervision, data collection, MRI scanning, wearable measurements, analysis, interpretation, and presentation of findings at national and international conferences.

The project is carried out as an equal collaboration between LUMC and Radboudumc, bringing together expertise in MRI development, wearable sensing, geriatrics, radiology, and neurology. The student will work at both locations, be employed by LUMC, and pursue the doctorate at Radboud University. The position is also part of the national MODEM consortium, which aims to improve understanding of dementia through fundamental research.

The environment is multidisciplinary and research-intensive, with MRI researchers, geriatricians, and radiologists working closely across institutions. An ICH-GCP training is available within LUMC.

Funding details

Paid PhD position with salary of €3,217 to €4,077 gross per month on a full-time basis (scale PRO, CAO UMC), 4-year fixed-term appointment at LUMC.

What's required

An academic university degree (wo) at the interface of technology and physiology or neurology is required. Candidates should have very good Dutch language skills at C1 level, spoken and written, and preferably have work or internship experience in Geriatrics, Radiology, or Neurology. The role also calls for strong collaboration, clear communication, flexibility, accuracy, and interest in new techniques and complex scientific questions.

How to apply

Apply via the AcademicTransfer application link. Submit your application before the deadline and follow the online procedure on the vacancy page.

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Professors

Professor at Leids Universitair Medisch Centrum

University Name
Country flag

Netherlands

Research Interests

Radiology

Medical Imaging

Magnetic Resonance Imaging

Biology

Physiology