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INSERM

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PhD Position: Mitochondrial Dynamics as a Regulator of Macrophage Function and Atherosclerosis Inserm in France

Degree Level

PhD

Field of study

Biology

Funding

Available

Deadline

Dec 31, 2026

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Country

France

University

INSERM

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Keywords

Biology
Macrophage Biology
Mitochondrial Biology
Medical Science
Atherosclerosis
Immunometabolism

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About this position

This PhD project investigates how mitochondrial dynamics shape macrophage function and contribute to atherosclerosis. The work focuses on MIRO1, a protein involved in mitochondrial transport and dynamics, and asks how it influences mitochondrial behaviour, macrophage metabolism, and inflammatory function in the context of vascular disease.

The successful candidate will join Inserm U1065 in Nice, within a research team studying the interplay between immunity, metabolism, and cardiovascular diseases. The project is centered on understanding how macrophages adapt to their microenvironment during atherosclerosis and how mitochondrial regulation may affect plaque development and progression.

Research activities will explore the connection between mitochondrial dynamics, metabolic reprogramming, and macrophage biology, with attention to the possible role of macrophages in circulating mitochondrial homeostasis. The position offers a multidisciplinary environment with laboratory meetings, seminars, scientific presentations, and interactions with national and international collaborators.

Funding details

Available

What's required

A Master's degree (MSc or equivalent) in Biology, Immunology, Cell Biology, Physiology or a related field is required. Applicants should have a strong interest in cellular biology, immunology, metabolism and cardiovascular diseases, along with good knowledge of molecular and cellular biology. Scientific rigour, critical thinking, good organizational skills, attention to detail, and the ability to work both independently and in a team are expected. Prior training and certification in laboratory animal science is strongly preferred and considered a major asset because of extensive mouse work; previous hands-on experience with mice is highly desirable. Additional advantages include experience with genetically modified mice or atherosclerosis models, macrophage biology and BMDM culture, flow cytometry, microscopy, mitochondrial metabolic analysis (Seahorse), and prior work in immunology or cardiovascular research. Excellent English is required; French is listed as basic.

How to apply

Send a CV with publication list, a short summary of research achievements, a motivation letter, and the names and email addresses of at least two references to the contact email. Use the email application link provided in the advert.

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