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CIC biomaGUNE

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PhD Position on Amyloid Protein Interactions with Chiral Gold Nanoparticles CIC biomaGUNE in Spain

Degree Level

PhD

Field of study

Molecular Biology

Funding

The position is a temporary full-time predoctoral contract with an initial duration of one year, renewable up to 36 months. It is funded within the CHIRAL-PRO project, supported by the European Research Council through Horizon Europe (GA 101166855).

Deadline

Nov 18, 2026

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Country

Spain

University

CIC biomaGUNE

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Keywords

Molecular Biology
Chemistry
Biomedical Engineering
Materials Science
Biophysics
Biology
Protein Chemistry
Nanophotonics
Atomic Force Microscopy
Gold Nanoparticles
Physics
Biomaterials

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About this position

CIC biomaGUNE is offering a PhD position in the Bionanoplasmonics Laboratory in San Sebastián, Spain, within the ERC-Synergy CHIRAL-PRO project. The research examines how amyloid proteins interact and assemble with chiral gold nanoparticles under different physicochemical conditions.

The doctoral researcher will investigate how metabolites, salt ions, pH, and membrane composition influence the nanoscale diffusion, forces, topography, and assembly dynamics of amyloid proteins. A central method will be time-lapse atomic force microscopy in liquid environments, enabling observation of protein oligomer formation and early aggregate development on biological membranes.

The project will then address how amyloid proteins interact with chiral gold nanoparticles of different morphologies, including the role of chirality-directed recognition. The final research stage will examine the combined effects of the physicochemical environment and chiral nanoparticles on amyloid protein dynamics and assembly in biologically relevant systems.

The work will be conducted in the Bionanoplasmonics Laboratory under the supervision of Prof. Luis M. Liz-Marzán and Dr. Pamina Winkler. CIC biomaGUNE is an international research center specializing in bionanomaterials, synthetic bioengineering, molecular imaging, and regenerative medicine, with advanced technical platforms, scientific seminars, and training opportunities for researchers.

Funding details

The position is a temporary full-time predoctoral contract with an initial duration of one year, renewable up to 36 months. It is funded within the CHIRAL-PRO project, supported by the European Research Council through Horizon Europe (GA 101166855).

What's required

A BSc and MSc in a relevant area of (bio-)chemistry, biophysics, molecular biology, or a related field. Candidates must be eligible to join a doctoral programme for the 2026/2027 academic year and must be enrolled in a doctoral programme when joining the center. Experience in protein chemistry and advanced bioimaging techniques such as atomic force microscopy is positively evaluated. Interest in multidisciplinary work, motivation to learn across diverse scientific areas, ability to work in an international environment, good interpersonal skills, and strong written and oral English communication skills are required.

How to apply

Submit a motivation letter explaining your interest, your CV, and the contact details of two academics who can provide references through the “Apply to this Job Offer” button on the advert page. Applications sent directly to the listed email address are not accepted.

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