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Nienke Bosschaart

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PhD position: Spectroscopic optical coherence tomography for non-invasive blood analysis University of Twente in Netherlands

Degree Level

PhD

Field of study

Biomedical Engineering

Funding

Full-time PhD position for four years with a gross monthly salary from €3,204 in the first year to €4,051 in the fourth year, plus holiday allowance, end-of-year bonus, pension scheme, and leave benefits.

Deadline

Nov 30, 2026

Country flag

Country

Netherlands

University

University of Twente

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Keywords

Biomedical Engineering
Microscopy
Optics
Medical Diagnostics
Optical Coherence Tomography
Biophotonics
Medical Science
Microcirculation
Clinical Engineering
Physics

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About this position

This PhD project develops spectroscopic optical coherence tomography (sOCT) for non-invasive hemoglobin analysis in newborns and adults. The research addresses the clinical challenge of anemia monitoring, where repeated invasive blood sampling can contribute to blood loss and delayed treatment decisions. The proposed sOCT approach aims to separate vascular from non-vascular tissue in the skin so that hemoglobin determination can be confined to blood-containing microvasculature.

You will work on a project that combines signal analysis model development, model validation, clinical system development, and patient-oriented application. The project is designed to move from fundamental optical analysis toward practical biomedical instrumentation, with an emphasis on making hemoglobin measurements more accurate and clinically useful. The work spans technology development, experimental validation, engineering, and clinical research.

You will be embedded in the Biomedical Photonic Imaging group at the University of Twente and collaborate closely with engineers, clinicians, and scientists. The group focuses on light-based medical technologies for research and diagnosis, including microscopy, wound healing, and mother-and-child care, with strong interests in microcirculatory blood flow, hemoglobin concentration, blood oxygenation, and light scattering. The environment is interdisciplinary and combines optical physics, biomedical engineering, and clinical evaluation in partnership with medical collaborators.

The position leads to a PhD dissertation over four years and includes doctoral training through the Twente Graduate School.

Funding details

Full-time PhD position for four years with a gross monthly salary from €3,204 in the first year to €4,051 in the fourth year, plus holiday allowance, end-of-year bonus, pension scheme, and leave benefits.

What's required

Applicants must have a master’s degree in Physics or Biomedical Engineering. Proven experimental skills in optics are required, and prior experience with OCT and hands-on optical system development is considered a strong asset. Candidates should have excellent coding, modelling and analysis skills, be comfortable moving between fundamental understanding, modelling, instrument development and experimental validation, and have strong interpersonal skills for research involving human participants. Careful and systematic working style, excellent organizational skills, good team spirit, fluency in English, and strong scientific writing skills are required. For non-Dutch applicants, an IELTS, TOEFL-iBT, or Cambridge CAE-C/CPE is required; if the applicant has a non-Dutch qualification and has not had secondary and tertiary education in English, a total IELTS band score of at least 6.5, TOEFL-iBT score of at least 90, or Cambridge CAE-C/CPE is required.

How to apply

Apply via the AcademicTransfer application page before 2026-11-30. Include a cover letter and CV with courses, grades, and any publications/references. Non-Dutch applicants should also include an IELTS, TOEFL-iBT, or Cambridge CAE-C/CPE result where applicable.

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Professors

Prof.dr.ir. at University of Twente

University Name
Country flag

Netherlands

Research Interests

Tissue Engineering

Pediatric Nutrition

Biomedical Optics

Blood Flow

Biophotonics