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University of Southampton

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PhD project in automating synthesis of isotope-labelled compounds for defence-relevant applications University of Southampton in United Kingdom

Degree Level

PhD

Field of study

Computer Science

Funding

Competition funded PhD project.

Deadline

Dec 18, 2026

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Country

United Kingdom

University

University of Southampton

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Keywords

Computer Science
Chemistry
Chemical Engineering
Predictive Modeling
Analytical Chemistry
Toxicology
Chemical Synthesis
Isotope Geochemistry

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About this position

PhD project at the University of Southampton on automating synthesis in the defence industry.

This postgraduate research project focuses on developing an integrated, automated platform for the rapid synthesis of isotope-labelled compounds for defence-relevant analytical and toxicological applications. The work combines synthetic chemistry, isotope chemistry, laboratory automation, analytical chemistry, and predictive modelling to investigate closed-loop approaches to isotope labelling.

Students will explore automated experimentation to rapidly screen and optimise reaction conditions while generating structured datasets of isotope-labelling reactions. These data will support models that connect reaction conditions and molecular structure to labelling outcomes, helping to plan synthetic routes to isotope-labelled compounds. Target molecules include analytical reference standards and compounds relevant to metabolism, toxicokinetics, and chemical-threat studies.

The project offers interdisciplinary training across organic synthesis, isotope chemistry, automation, analytical measurement, large-scale chemical datasets, predictive modelling, and 3D printing. It is designed for applicants who want a broad combination of practical laboratory skills and digital/data-driven research experience.

Funding is listed as competition funded. The posted entry requirement is a 2:1 honours degree. The closing date shown on the project page is 18 December 2026.

This opportunity is hosted by the University of Southampton in the United Kingdom. Interested applicants should read the project page carefully, check the full entry requirements and funding details, and apply via the university’s postgraduate research application process.

Funding details

Competition funded PhD project.

What's required

Applicants should have a 2:1 honours degree. The project is suitable for students interested in organic synthesis, isotope chemistry, laboratory automation, analytical chemistry, large-scale chemical datasets, predictive modelling and 3D printing. Interdisciplinary skills development is highlighted, so a strong interest in both experimental and data-driven research is important.

How to apply

Review the project details and full entry requirements on the University of Southampton project page, then apply through the postgraduate research application process. Check the funding and how-to-apply sections before submitting your application.

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Prepare your application

Review drafts and confirm requirements with the university.