PhD Studentship: Role of Non-canonical Autophagy in the Liver Response to Unhealthy Western Diets University of East Anglia in United Kingdom

PhD opportunity at Quadram Institute Bioscience in Norwich, United Kingdom, within the Norwich Research Park Biosciences Doctoral Training Programme (NRPDTP). The project is titled Role of non-canonical autophagy in liver lipid metabolism in response to unhealthy diets and sits at the intersection of autophagy, liver lipid metabolism, fatty liver disease, obesity, hepatocyte biology, LC3-associated phagocytosis, cell biology, molecular biology, immunology , and translational biomedical research....

[Fully funded 4-year Norwich Research Park Biosciences Doctoral Training Partnership PhD studentship including payment of tuition fees, a stipend for living expenses at the 2026/27 rate of £21,805, and a Research Training Support Grant of £5,000 per year.] This PhD studentship at the University of East Anglia is offered through the Norwich Research Park Biosciences Doctoral Training Programme (NRPDTP) and focuses on the role of non-canonical autophagy in liver lipid metabolism in response to unh...

PhD opportunity in immunology and molecular biology at the Medical Research Council (Cambridge), Laboratory of Molecular Biology. The project, supervised by Dr Patrycja Kozic, asks whether perforin-2 (Mpeg1) forms pores in two orientations and how this ancient MACPF/CDC family protein is regulated during immune responses. The research focuses on perforin-2 function in dendritic cells and macrophages, especially its roles in attacking intravacuolar pathogens and enabling cytosolic antigen deliver...

PhD opportunity at the Laboratory of Molecular Biology in Cambridge, United Kingdom, focused on TRIM21 , intracellular antibody immunity, and the degradation of viruses and protein aggregates . The project explores how TRIM21, a cytosolic E3 ligase and antibody receptor, is activated and regulated, how it recruits different E2 enzymes, and how it can direct substrates to both the proteasome and autophagy. The research is highly relevant to molecular biology , immunology , biophysics , and struct...

Funded PhD opportunity at the MRC Laboratory of Medical Sciences (LMS), London, United Kingdom. This project, supervised by Dr Chi Kin Wong and Dr Will Scott, investigates the long-term effects of GLP-1 medicines on immunometabolic fitness . The research asks how GLP-1 receptor signalling influences chronic inflammation, immune function, and metabolic stress beyond its established effects on weight loss and glucose control. The project will use mouse models , diverse transgenic approaches , and ...