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Publisher
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University of East Anglia

PhD Studentship: Transgenerational Epigenetic Inheritance of Responses to Environmental Stress University of East Anglia in United Kingdom

Degree Level

PhD

Field of study

Physiology

Funding

Full funding available

Deadline

Oct 1, 2026

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Country

United Kingdom

University

University of East Anglia

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Keywords

Physiology
Evolutionary Biology
Ecology
Environmental Science
Biology
Phenotypic Plasticity
Adaptation
Stress Biology
Rna-seq
Epigenetic
Abiotic Stress
Genomic
Natural Selection
Elegans
Bioinformatic

About this position

This PhD project at the University of East Anglia investigates the mechanisms of transgenerational epigenetic inheritance and cellular stress responses in Caenorhabditis elegans. The research addresses how populations adapt to rapidly changing environments due to anthropogenic climate change, focusing on whether critical cellular stress responses can be transmitted non-genetically across generations. The project will determine if such inheritance enhances population resistance to environmental stress and individual Darwinian fitness, and will explore the mechanistic basis using advanced techniques such as single-cell RNA sequencing (scRNA-seq) and candidate regulator screening.

The successful candidate will gain comprehensive training in experimental design, statistical analysis, bioinformatics, scientific writing, and presentation, as well as expertise in evolutionary biology, cell biology, and physiological techniques. Participation in external training courses, conferences, seminars, research discussion groups, and journal clubs is also included. Applicants should have a strong interest in evolution, ecology, genetics, and stress response biology, and must hold at least a UK equivalent Bachelors (Honours) 2:1 degree in Biological Sciences.

English language proficiency is required (IELTS 6.5 overall, 6 in each category). The position is full-time and starts on 1 October 2026. Funding is provided through an ARIES studentship, covering tuition fees, a maintenance stipend (£20,780 p.a. for 2025/26), and a research training and support grant (RTSG). A limited number of studentships are available for international applicants, with the difference between 'home' and 'international' fees waived, though relocation, visa, and health surcharge costs are not covered.

Funding details

Full funding including tuition fees and living expenses is available for this position. The scholarship covers all educational costs and provides a monthly stipend.

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