Post-doctoral Fellow in Organic Chemistry Lund University in Sweden

Post-doctoral Fellow in Organic Chemistry at Lund University , Sweden. This postdoctoral opening sits at the interface of organic chemistry and chemical biology , with a strong focus on targeted protein degradation in bacteria. The project develops a modular chemical platform for BacPROTACs as a new strategy against antimicrobial resistance (AMR), aiming to design bifunctional molecules that recruit bacterial proteolytic machinery such as the ClpC:ClpP system to selectively degrade essential pro...

This postdoctoral project at Leiden University focuses on covalent small-molecule inhibitor discovery for emerging cancer targets. The work is rooted in chemical proteomics and drug discovery for proteins involved in immune-oncology that are considered challenging to address with conventional small molecules. The successful researcher will develop and optimize electrophilic lead compounds, then design bifunctional analogues intended to induce protein degradation. The role combines synthetic and ...

Leiden University / Leiden University Medical Center / Leiden Early Drug Discovery and Development (LED3) are advertising a postdoctoral position in medicinal chemistry and chemical biology focused on a synthetic lethality target . The project is described as an exciting collaboration with Sylvie Noordermeer at Leiden University Medical Center, who pioneered the discovery of the synthetic lethal nature of the target. The lab environment is presented as highly collaborative and discovery-oriented...

📢 A fully funded PhD studentship is available in the group of Daniele Castagnolo at University College London (UCL), jointly supervised with Dr Dimitrios Evangelopoulos, through the 2027 cohort of the CDT in Engineering Solutions for Antimicrobial Resistance (CDT AMR). The project will focus on the development of novel antibacterial agents to combat antimicrobial resistance (AMR), bringing together medicinal chemistry, drug discovery, microbiology, and biocatalysis. Research will be based primar...

CNRS Research Director Anton Granzhan is recruiting for an 18-month postdoctoral position in bioorganic chemistry and chemical biology at LCBPT (CNRS – Université Paris Cité, Paris, France). The project builds on a recent discovery of small molecules that selectively bind DNA three-way junctions and show toxicity against certain cancer cells. The next stage is to design a new generation of macrocyclic TWJ ligands and heterobifunctional probes to investigate how these molecules act in cells. Suit...