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Post-doctoral position in Chemical Biology (H/F) CNRS in France
Degree Level
Postdoc
Field of study
Biochemistry
Funding
CDD d'1 an; remuneration from 3131€ gross per month.
Deadline
Nov 12, 2026
Country
France
University
CNRS
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About this position
This post-doctoral project at CNRS focuses on m6A RNA modification and the development of new RNA modification strategies aimed at improving mRNA vaccine performance. The work sits at the interface of chemistry and biology and centers on the design of original chemo-enzymatic approaches for site-specific RNA modification.
The selected researcher will contribute to three connected research directions:
- developing chemo-enzymatic methods for precise RNA modification using chemoenzymatic strategies and induced chemical proximity (ICP),
- investigating how RNA modifications influence mRNA-based therapeutics,
- applying the methods to modify mRNA vaccines.
The project is based in the team “Chemistry of RNAs, Nucleosides, Peptides & Heterocycles” within the Laboratoire de Chimie et de Biochimie pharmacologiques et toxicologiques (LCBPT) at Université Paris Cité in Paris. The advertised work is specifically in RNA chemistry, combining synthetic chemistry with biological application in therapeutic RNA research.
The position is hosted by a research group working on nucleic acids and related chemical biology themes, offering an environment centered on organic synthesis, analytical characterization, purification, and translational RNA research.
Funding details
CDD d'1 an; remuneration from 3131€ gross per month.
What's required
A PhD in organic chemistry is required. The candidate should have a strong background in organic synthesis, characterization methods including 1D and 2D NMR and MS, and purification techniques such as column chromatography and HPLC. Experience in nucleosides and nucleotides chemistry would be appreciated. The applicant should be highly motivated for research at the chemistry-biology interface, able to work independently, and have good written and oral communication skills. French language level: threshold.
How to apply
Apply on the employer’s site via the provided application link. Review the detailed CNRS posting before submitting your application. Submit before the deadline of 2026-11-12.
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