Postdoc en biologie structurale des amyloïdes : bases moléculaires des tauopathies (projet ERC) CNRS in France

PhD opportunity in Protein Aggregates and Neurodegeneration at the Medical Research Council (Cambridge), Laboratory of Molecular Biology, with Dr H McMahon. This project explores how protein aggregates accumulate, become toxic to brain cells, and spread in neurodegenerative disease. Two related PhD projects are available in the McMahon group. One focuses on aggregate uptake mechanisms , including Aggregation-Dependent Endocytosis, receptor identification, aggregate size effects, and ways to prev...

PhD opportunity in Structure-Function Analysis of Stress Signaling at the Medical Research Council (Cambridge), Laboratory of Molecular Biology, with supervision by Dr A Bertolotti. The lab studies stress signaling and the integrated stress response (ISR), with a strong focus on how cells protect themselves from misfolded proteins and how these pathways may be harnessed to improve resilience in disease. The project is especially relevant to neurodegenerative diseases such as Alzheimer’s disease,...

The Debler Laboratory at Thomas Jefferson University is recruiting a postdoctoral scientist for a project at the intersection of biochemistry and structural biology. The position focuses on understanding the mechanism of macromolecular machines and assemblies using high-end structural approaches, with particular emphasis on x-ray crystallography and/or cryo-electron microscopy. The lab is described as well funded by NIH, strongly equipped with state-of-the-art instrumentation, and embedded in a ...

This fully funded PhD position at the VIB–VUB Center for Structural Biology offers an exciting opportunity to join the laboratory of Dr. Anastassia Vorobieva, a leader in the de novo design of transmembrane β-barrel nanopores. The research focuses on engineering and characterizing membrane proteins, nanopores, and ion channels for in vitro bioelectronic applications, sitting at the interface of protein design and applied technology. The successful candidate will learn and apply state-of-the-art ...

PhD opportunity in mechanism of transcription-coupled splicing at the Medical Research Council Laboratory of Molecular Biology in Cambridge, United Kingdom , supervised by Dr Suyang Zhang . The project focuses on how RNA polymerase II and the spliceosome communicate during co-transcriptional splicing to ensure accurate gene expression in eukaryotic cells. The lab studies the molecular mechanisms coordinating transcription and pre-mRNA splicing in human cells, including direct interactions betwee...