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University of Oxford

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Postdoctoral Research Associate in Natural Product Chemistry for Safer Antifungals University of Oxford in United Kingdom

Degree Level

Postdoc

Field of study

Pharmacology

Funding

Full-time postdoctoral research position at Research Grade 7, with a salary of £39,424–£43,984 per annum. The appointment is available for 36 months, from 1 January 2027 until 31 December 2029.

Deadline

Nov 11, 2026

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Country

United Kingdom

University

University of Oxford

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Keywords

Pharmacology
Biochemistry
Chemistry
Biology
Chemical Biology
Natural Products Chemistry
Natural Product Synthesis

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About this position

The University of Oxford is recruiting a Postdoctoral Research Associate in Natural Product Chemistry for the Oxford Martin Programme on Safer Antifungals. Based at the Life and Mind Building on South Parks Road and the Department of Pharmacology on Mansfield Road, the project aims to discover a new generation of naturally inspired products for combating fungal diseases in agriculture and medicine.

The research focuses on microscopic freshwater bdelloid rotifers, which naturally protect themselves from fungi using genes acquired through horizontal DNA transfer. The postdoctoral researcher will help translate this discovery into a platform for identifying safer antifungal compounds.

The work brings together biology, pharmacology, chemistry and medicine, with links to the Ineos Oxford Institute and Oxford University Innovation. Research activities include bioactivity-guided extraction and purification of antifungal compounds, elucidation of compound structures and mechanisms of action, investigation of biosynthetic origins and candidate pathways, and chemical or biosynthetic diversification of promising compounds.

The researcher will also perform biological activity and toxicity assays, reconstruct bioactive molecules through biosynthetic approaches, and communicate findings through scientific publications and future research translation. The role offers an interdisciplinary environment involving laboratory research, natural product discovery, chemical biology and innovation.

Funding details

Full-time postdoctoral research position at Research Grade 7, with a salary of £39,424–£43,984 per annum. The appointment is available for 36 months, from 1 January 2027 until 31 December 2029.

What's required

Applicants should have a PhD in chemistry, biochemistry, biosynthetic chemistry, chemical biology or a related discipline, with strong research expertise and specialist knowledge in a relevant area. Prior laboratory experience is required in one or more of purifying chemicals from complex biological mixtures, elucidating chemical structures of biologically active molecules, or using genetic and synthetic-biology approaches to natural product synthesis, including biosynthetic pathway elucidation and reconstruction of bioactive molecules. Applicants should demonstrate initiative in developing research ideas and methodologies, excellent written and verbal communication skills, and the ability to work effectively in a multidisciplinary team and advise or supervise other team members. Strong interest or experience in research translation and innovation is desirable.

How to apply

Apply online through the University of Oxford e-recruitment system. Upload a supporting statement and CV with the application before 12:00 noon on 11 November 2026.

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