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Daniel Kober

3 months ago

Postdoctoral Researcher in Structural Biology and High-Throughput Screening at UT Southwestern Medical Center UT Southwestern Medical Center in United States

Degree Level

Postdoc

Field of study

Biochemistry

Funding

Postdoctoral research positions in the Kober Lab at UT Southwestern Medical Center; funding details are not specified in the post or linked text.

Deadline

Expired

Country flag

Country

United States

University

University of Texas Southwestern Medical Center

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Keywords

Biochemistry
Chemistry
Biology
Structural Biology
High-throughput Screening
Medical Science
Functional Biology
Protease

About this position

UT Southwestern Medical Center’s Kober Lab in Dallas, Texas is recruiting two postdoctoral researchers in biochemistry and related areas. The lab, led by Daniel Kober, Ph.D. (Assistant Professor, Department of Biochemistry), studies how protein homeostasis—the maturation and turnover of enzymes—interacts with lipid metabolism. The research is highly interdisciplinary and uses structural biology, enzymatic reconstitution assays, cell biology, and discovery-based screening.

One postdoc will focus on developing and implementing high-throughput screens for novel inhibitors of serine proteases in the secretory system, including chemical screening, mechanism-of-action studies, and in vitro potency assays in collaboration with the HTS core facility. The second postdoc will focus on structural and functional characterization of these enzymes, ideally for someone with a background in structural biology who wants to expand into functional biology, or vice versa.

The post is aimed at motivated scientists who enjoy tackling complex biological problems through multiple mechanistic approaches. The lab values interdisciplinary research, creativity, and experimental rigor. No deadline or funding package is specified in the post, but this is a formal postdoctoral researcher opening at UT Southwestern Medical Center.

How to apply: prospective postdocs should contact Dr. Kober with a statement of interest, CV, and contact information for three references. You can also review the lab website and the official job posting for additional details.

Funding details

Postdoctoral research positions in the Kober Lab at UT Southwestern Medical Center; funding details are not specified in the post or linked text.

What's required

Applicants should have a background in structural biology for the enzyme characterization position, or experience in functional biology; the lab also welcomes candidates interested in expanding across these areas. The post emphasizes interdisciplinary research, creativity, and experimental rigor. Prospective postdocs should send a statement of interest, CV, and contact information for three references.

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Professors

Assistant Professor, Dept of Biochemistry

University Name
Country flag

United States

Research Interests

Cell Biology

Biochemistry

Proteostasis

Allosteric Regulation

Lipid Chemistry