Daniel Kober
Assistant Professor, Dept of Biochemistry
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About
Dr. Daniel Kober is an Assistant Professor at The University of Texas Southwestern Medical Center, USA. His research primarily focuses on structural biology and cell signaling, with recent articles exploring substrate selectivity of site-one protease, the role of oxygen sensor DosP in c-di-GMP phosphodiesterase regulation, and the development of monoclonal antibodies related to lipid homeostasis. He is actively contributing to advancements in understanding cholesterol sensing and the interactions of proteins linked to neurodegenerative diseases.
Positions (1)
Daniel Kober
UT Southwestern Medical Center
UT Southwestern Medical Center’s Kober Lab in Dallas, Texas is recruiting two postdoctoral researchers in biochemistry and related areas. The lab, led by Daniel Kober, Ph.D. (Assistant Professor, Department of Biochemistry), studies how protein homeostasis —the maturation and turnover of enzymes—interacts with lipid metabolism . The research is highly interdisciplinary and uses structural biology , enzymatic reconstitution assays , cell biology , and discovery-based screening . One postdoc will focus on developing and implementing high-throughput screens for novel inhibitors of serine proteases in the secretory system, including chemical screening, mechanism-of-action studies, and in vitro potency assays in collaboration with the HTS core facility. The second postdoc will focus on structural and functional characterization of these enzymes, ideally for someone with a background in structural biology who wants to expand into functional biology, or vice versa. The post is aimed at motivated scientists who enjoy tackling complex biological problems through multiple mechanistic approaches. The lab values interdisciplinary research , creativity , and experimental rigor . No deadline or funding package is specified in the post, but this is a formal postdoctoral researcher opening at UT Southwestern Medical Center. How to apply: prospective postdocs should contact Dr. Kober with a statement of interest , CV , and contact information for three references . You can also review the lab website and the official job posting for additional details.
Articles (9)
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2025
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2024
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2024
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2024
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2024
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2024
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2021
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2020
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2020
Collaborators (4)
Noam Zelcer
University of Amsterdam
Arun Radhakrishnan
Associate Professor
University of Texas Southwestern Medical Center
Pankaj Kumar
University of Texas Southwestern Medical Center
Michael Strickland
Washington University in St. Louis
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