Postdoctoral Researcher: Microfluidic Segmented Flow for High-Throughput NMR Leiden University in Netherlands

The Metabolomics and Analytics Center (MAC) at Leiden University is seeking a Postdoctoral Researcher to advance research in microfluidic segmented flow for high-throughput NMR and metabolomics. This innovative project aims to develop a biotechnology screening platform for molecular profiling, bridging multiple scientific fields and applications. Building on previous collaborations with dsm-firmenich, the team has developed automated systems for stopped flow injection and NMR detection of metabolites, featuring robotics, custom flow cells, and precise fluidic control.

The successful candidate will focus on upgrading automation control and deepening understanding of microfluidics, specifically the stability of organic solvent slugs in push solvents and flow-cell design. Responsibilities include developing novel NMR flow-cells, enhancing the automation of liquid handling robotics (including pump control, slug detection, and feedback loops), and demonstrating the improved system's potential in biotechnology and human health applications. The research will be conducted in collaboration with the Analytical Sciences department of dsm-firmenich in Delft, where two systems for segmented flow high-throughput NMR are installed.

Applicants must have a PhD in analytical chemistry, microfluidics, chemical engineering, robotics, biomedical engineering, or a related field. Experience in microfluidics, especially segmented slug flow, is essential. Programming proficiency (Python and LabView preferred), and an interest in metabolomics, programming, and NMR are desired. Good to excellent English proficiency is required.

The MAC is a pioneer in metabolomics, combining advanced technologies, innovative sample preparation, robotics, and computational expertise. The Faculty of Science at Leiden University offers a dynamic international environment, and the LACDR is a leading drug research institute. The position is full-time for one year, with possible extension up to four years based on performance and compatibility. Salary ranges from €3546 to €5538 gross per month, plus holiday and end-of-year bonuses, training, and career development opportunities. Employment conditions follow the Dutch Universities' Collective Labour Agreement.

Leiden University values an inclusive academic community where all staff and students are respected and can fully develop their talents. For further information, contact Prof. Dr. Thomas Hankemeier ([email protected]). Applications must be submitted online, including a motivation letter and full CV, quoting the vacancy number. Only applications received before May 15, 2026 will be considered.