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Marcin Poręba

2 months ago

Research Assistant (PhD Student) in Protease Biology for Antibody-Drug Conjugate Research Wrocław University of Science and Technology in Poland

Degree Level

PhD

Field of study

Cell Biology

Funding

Available

Deadline

Sep 9, 2026

Country flag

Country

Poland

University

Wrocław University of Scince and Technology

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Keywords

Cell Biology
Chemistry
Biomedical Engineering
Biology
Medical Science
Cell Culture Techniques
Protease
Cancer Biomarkers
Solid Tumor

About this position

Research Assistant (PhD Student) at the Wrocław University of Science and Technology, Faculty of Chemistry, in the Department of Biological Chemistry and Bioimaging.

This position is part of the PACMAN project: “Personalized antibody-drug conjugates activated by matrix metalloproteinases for solid tumors”. The project is led by Marcin Poręba (PhD, DSc, Prof. of WUST) and is hosted within the Virtual Research Institute (WIB), managed by Łukasiewicz Research Network – PORT.

The research is focused on proteases involved in the development of solid tumors, especially matrix metalloproteinases and related proteolytic mechanisms. The work includes investigation of neutrophil heterogeneity based on protease activity, toxicity assessment of ADC conjugates toward neutrophils, recombinant protease substrate specificity analysis, and studies of proteases in cancer cells using chemical probes. The broader project aims to develop a new class of antibody-drug conjugates that can be selectively activated extracellularly in the tumor microenvironment without internalization.

This is a full-time temporary research appointment at R1 level (First Stage Researcher), advertised as a PhD student position. The post runs for 12 months initially, with the possibility of extension by 32 months after positive performance evaluation, for a total of 44 months. The salary is PLN 5,393 gross per month plus an additional thirteenth salary.

Eligibility highlights include a Master’s degree in Biotechnology, Chemistry, or a related field, enrolment in the Doctoral School, practical knowledge of cell biology and in vitro culture methods, experience with immune cells isolated from whole blood, and hands-on work with proteolytic enzymes and kinetic studies using recombinant proteins. Excellent English is required.

Applicants should submit the required competition documents by email to [email protected] no later than 2026-09-09 23:55 (Europe/Warsaw). The application should reference As15/W3/08/2026_ENG. Required documents include a cover/application letter, CV, proof of degree, self-report on research/teaching/organisational activity, publication list, scientific internship list and descriptions, and the required personal-data and eligibility statements.

The position is based in Wrocław, Poland, and offers a strong translational research environment with access to preclinical validation, interdisciplinary collaboration, and international exchange opportunities at a reputable technical university.

Funding details

Available

What's required

Master’s degree in Biotechnology, Chemistry, or a related field is required, together with enrolment in the Doctoral School. Applicants should have knowledge of basic research techniques in cell biology and in vitro cell culture, ability to work with specific immune cells isolated from whole blood, and experience working with proteolytic enzymes, including kinetic studies using recombinant proteins. Excellent English is required. Candidates must also comply with the WIB Programme non-competition policy. The selection process will consider scientific and professional experience, relevance of previous research to the project, scientific achievements such as publications and project participation, international experience and mobility, teamwork and communication skills, and alignment of the candidate’s plans with the research team.

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Professors

Prof. of WUST at Wrocław University of Science and Technology

University Name
Country flag

Poland

Research Interests

Pharmacy

Statistics

Medical Science

Biomedical Engineering

Biology