Achim Lother

PhD position available in Cardiovascular Epigenetics at the University of Freiburg within the FOR6051 programme, The Interstitium: a Key Determinant of Cardiac Function . The project (P6-2) is hosted at the Institute for Experimental and Clinical Pharmacology and Toxicology and is supervised by Achim Lother with a joint project involving Rémi Peyronnet . The research investigates how altered hemodynamics in heart failure and atrial fibrillation affect epigenetic regulation of gene expression, with a focus on mechanosensitive ion channels , cardiac remodeling, and arrhythmogenesis. Research activities include translational cardiac disease models, pharmacology, molecular biology, wet-lab omics technologies, and bioinformatics. The project mentions in vivo experimental research, cell isolation, flow cytometry, transcriptomics, epigenetics, RNA-seq, ChIP-seq, ATAC-seq, and proteomics with bioinformatics analysis. Eligible backgrounds include (molecular) medicine, biochemistry, (technical) biology, pharmacy, and bioinformatics. Applicants should have a strong motivation, a solid background in cardiac biology and/or epigenetics, and preferably prior bioinformatics experience. English proficiency at B2 or higher is required. The application window is open until 07 June 2026 . Applications are submitted via the SGBM portal under the FOR6051 track. Required documents include personal/contact details, bachelor and master transcripts/certificates, proof of English proficiency, contact details of two referees, and a motivation statement with research interests.