Manfred Jung

Professor for Pharmaceutical Chemistry, www.jungm.de

University of Freiburg

Germany

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Articles (11)

Year:

2024

Year:

2023

Year:

2023

Year:

2023

Year:

2022

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2022

Year:

2022

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2022

Year:

2022

Year:

2021

Year:

2021

Collaborators (12)

Wolfgang Sippl

Professor

Martin Luther University Halle-Wittenberg

GERMANY

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Claudia Jessen‐Trefzer

GERMANY

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Lutz Hein

Prof. Dr.

University of Freiburg

GERMANY

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Bernhard Kuster

GERMANY

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Matthias Schiedel

Professor

Technische Universität Braunschweig

GERMANY

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Hans-Peter Deigner

Professor Molecular Pharmacology, Dean (2014-)

GERMANY

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Finn Kristian Hansen

University of Bonn

GERMANY

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Matthias Gehringer

Eberhard Karls Universität Tübingen

GERMANY

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Bernd Fleischmann

Professor

Rheinische Friedrich-Wilhelms-Universität Bonn

GERMANY

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Christian Ochsenfeld

Professor

Ludwig-Maximilians-Universität München

GERMANY

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Mohamed Abdelsalam

Martin Luther University Halle-Wittenberg

GERMANY

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Achim Lother

Attending physician and Research group leader at University of Freiburg

University of Freiburg

GERMANY

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Manfred Jung

Research Interests

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Articles (11)

Design and synthesis of bioreductive prodrugs of class I histone deacetylase inhibitors and their biological evaluation in virally transfected acute myeloid leukemia cells

Continuous Fluorescent Sirtuin Activity Assay Based on Fatty Acylated Lysines

Photoreductive β-aminoalkylation with amino acids affords functionalized γ-aminoketones for nucleoside mimics

Total synthesis and biological evaluation of histone deacetylase inhibitor WF-3161

Design, Synthesis and Biological Characterization of Histone Deacetylase 8 (HDAC8) Proteolysis Targeting Chimeras (PROTACs) with Anti-Neuroblastoma Activity

Comparison of Cellular Target Engagement Methods for the Tubulin Deacetylases Sirt2 and HDAC6: NanoBRET, CETSA, Tubulin Acetylation, and PROTACs

Histone Deacetylase 6 Inhibitor JS28 Prevents Pathological Gene Expression in Cardiac Myocytes

Frontiers in Medicinal Chemistry 2022 Goes Virtual

Development of hetero-triaryls as a new chemotype for subtype-selective and potent Sirt5 inhibition

Lineage-Selective Disturbance of Early Human Hematopoietic Progenitor Cell Differentiation by the Commonly Used Plasticizer Di-2-ethylhexyl Phthalate via Reactive Oxygen Species: Fatty Acid Oxidation Makes the Difference

BET Proteins Regulate Expression of Osr1 in Early Kidney Development

Collaborators (12)

Wolfgang Sippl

Claudia Jessen‐Trefzer

Lutz Hein

Bernhard Kuster

Matthias Schiedel

Hans-Peter Deigner

Finn Kristian Hansen

Matthias Gehringer

Bernd Fleischmann

Christian Ochsenfeld

Mohamed Abdelsalam

Achim Lother

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