Ajay Goel

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Professor and Chair, Dept. of Molecular Diagnostics and Experimental Therapeutics; Associate Director of Basic Sciences, City of Hope Comprehensive Cancer Center

Beckman Research Institute, City of Hope

United States

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About

Ajay Goel is a Professor and Chair in the Department of Molecular Diagnostics and Experimental Therapeutics at the Beckman Research Institute, City of Hope, USA. He also serves as the Associate Director of Basic Sciences at the City of Hope Comprehensive Cancer Center. His research focuses on advancing early diagnosis, prevention, and treatment strategies for pancreatic and colorectal cancers, with recent publications exploring the role of microbiome dysbiosis and novel therapeutic compounds.

Recent Grants

Grant: Close

Noncoding RNA Biomarkers for Noninvasive and Early Detection of Pancreatic Cancer

Open Date: 2017-09-01

Close Date: 2022-07-31

Grant: Close

MicroRNA Biomarkers for Determining Treatment Response in Colorectal Cancer

Open Date: 2016-09-01

Close Date: 2021-07-31

Grant: Close

Development of microRNA Biomarkers For Noninvasive Detection of Colorectal Cancer

Open Date: 2015-07-01

Close Date: 2020-06-30

Grant: Close

Aspirin and Cancer Prevention in Lynch Syndrome: From Cell to Population Data

Open Date: 2014-09-23

Close Date: 2019-06-30

Grant: Close

Next Generation Sequencing-Based Approaches for the Development of Epigenetic Biomarkers for Predicting Therapeutic Outcome in Patients With Colorectal Cancer

Open Date: 2014-08-20

Close Date:

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2023

Collaborators (19)

André Gerber

Professor

University of Surrey

UNITED KINGDOM

Ajay Goel

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About

Recent Grants

Articles (19)

Intra-Tumoral CD8+:CD3+ Lymphocyte Density Ratio in Appendix Cancer Is a Tumor Volume- and Grade-Independent Predictor of Survival

Advances in pancreatic cancer early diagnosis, prevention, and treatment: The past, the present, and the future

Fusobacterium nucleatum Is Associated with Tumor Characteristics, Immune Microenvironment, and Survival in Appendiceal Cancer

Oligomeric Proanthocyanidins Reverse Lenvatinib Resistance in Hepatocellular Carcinoma Through ITGA3-Mediated Pathway

Microbiome dysbiosis, neutrophil recruitment and mesenchymal transition of mesothelial cells promotes peritoneal metastasis of colorectal cancer

Correction: Roy et al. Metformin and ICG-001 Act Synergistically to Abrogate Cancer Stem Cells-Mediated Chemoresistance in Colorectal Cancer by Promoting Apoptosis and Autophagy. Cancers 2022, 14, 1281

Ultrafast bisulfite sequencing detection of 5-methylcytosine in DNA and RNA

The anticancer effects of Aronia berry extract are mediated by Chk1 and p53 in colorectal cancer

Combined treatment with Aronia berry extract and oligomeric proanthocyanidins exhibit a synergistic anticancer efficacy through LMNB1‐AKT signaling pathways in colorectal cancer

The LAMB3-EGFR signaling pathway mediates synergistic Anti-Cancer effects of berberine and emodin in Pancreatic cancer

Ginseng mediates its anticancer activity by inhibiting the expression of DNMTs and reactivating methylation-silenced genes in colorectal cancer

Intratumoral Malassezia globosa Levels Predict Survival and Therapeutic Response to Adjuvant Chemotherapy in Patients With Pancreatic Ductal Adenocarcinoma

The Non-Coding RNA Journal Club: Highlights on Recent Papers—12

A liquid biopsy signature for predicting early recurrence in patients with gastric cancer

Molecular and Sociodemographic Colorectal Cancer Disparities in Latinos Living in Puerto Rico

Curcumin and Andrographis Exhibit Anti-Tumor Effects in Colorectal Cancer via Activation of Ferroptosis and Dual Suppression of Glutathione Peroxidase-4 and Ferroptosis Suppressor Protein-1

Curcumin-Mediated Resistance to Lenvatinib via EGFR Signaling Pathway in Hepatocellular Carcinoma

Genome-wide methylation profiling identifies a novel gene signature for patients with synchronous colorectal cancer

Andrographis Reverses Gemcitabine Resistance through Regulation of ERBB3 and Calcium Signaling Pathway in Pancreatic Ductal Adenocarcinoma

Collaborators (19)

André Gerber

Shizuka Uchida

José Perea

Kunhong Xiao

Johanna DiStefano

Alessio Naccarati

Jing Jin

Yoh Asahi

Xiao-bo Zhong

Mirolyuba Ilieva

Luis Bujanda

William LaFramboise

Ling Yang

Barbara Pardini

Alexander Serganov

Leandro Castellano

Alessandro Mannucci

Qing Dai

Simon Conn

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