Alex Loukas

Distinguished Professor

James Cook University Cairns Campus

Australia

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About

Dr. Alex Loukas is a Distinguished Professor at James Cook University - Cairns Campus, Australia. His research focuses on parasitology and immunology, with recent articles exploring topics such as gene editing in liver flukes, the anthelmintic potential of stonefish toxins, and the development of vaccines against helminths. His work contributes significantly to the understanding of parasite-host interactions and the development of novel therapeutic strategies.

Articles (20)

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2020

Collaborators (16)

John Miles

James Cook University

AUSTRALIA

Alex Loukas

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Articles (20)

Helminth extracellular vesicles co-opt host monocytes to drive T cell anergy

Gene Editing of a Carcinogenic Liver Fluke Tetraspanin Impairs Parasite Surface Biogenesis and Extracellular Vesicle Uptake by Human Host Cells

The Anthelmintic Activity of Stonefish (Synanceia spp.) Ichthyocrinotoxins and Their Potential as Novel Therapeutics

Evaluation of the recombinant protein <i>Sh</i>-TSP-2 for the serological diagnosis of imported urogenital schistosomiasis and comparison with commercially available tests.

Proteomic characterization and comparison of the infective and adult life stage secretomes from Necator americanus and Ancylostoma ceylanicum.

Hookworm vaccines: current and future directions

Characterization of Spirulina-derived extracellular vesicles and their potential as a vaccine adjuvant.

Mechanistic insights into liver-fluke-induced bile-duct cancer

Schistosoma heamatobium tetraspanins TSP-2 and TSP-6 induce Dendritic Cells maturation, cytokine production and T helper cells differentiation in vitro.

Ulcerative colitis: clinical biomarkers, therapeutic targets, and emerging treatments.

Identification of an inter-cysteine loop potentially involved in the activity of Opisthorchis viverrini-granulin-1

Excretory/Secretory Proteome of Females and Males of the Hookworm <i>Ancylostoma ceylanicum</i>

Transgenesis in parasitic helminths: a brief history and prospects for the future

Administration of Hookworm Excretory/Secretory Proteins Improves Glucose Tolerance in a Mouse Model of Type 2 Diabetes

Oral Peptide Vaccine against Hookworm Infection: Correlation of Antibody Titers with Protective Efficacy

A netrin domain-containing protein secreted by the human hookworm Necator americanus protects against CD4 T cell transfer colitis.

Hepatobiliary morbidities detected by ultrasonography in Opisthorchis viverrini-infected patients before and after praziquantel treatment: a five-year follow up study.

Proteomic approaches to drive advances in helminth extracellular vesicle research.

Randomized, Placebo Controlled Trial of Experimental Hookworm Infection for Improving Gluten Tolerance in Celiac Disease.

Identification and Characterization of a Peptide from the Stony Coral <i>Heliofungia actiniformis</i>.

Collaborators (16)

John Miles

Norelle L. Daly

David J Miller

John Hawdon

Luke Becker

Maria J. Perteguer

Rozita Takjoo

Annalisa RADEGHIERI

Waleed M. Hussein

Sergej Djuranovic

Phurpa Wangchuk

Maria Elena Bottazzi

Peter Nejsum

Makedonka Mitreva

Javier Sotillo

Paul J. Brindley

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