Andreas Joerger

Goethe University Frankfurt

Germany

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Articles (16)

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2024

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2024

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2024

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2024

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2023

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2023

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2023

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2023

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2023

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2022

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2022

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2021

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2021

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2021

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2021

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2021

Collaborators (13)

Stefan Knapp

Goethe University Frankfurt

GERMANY

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Mark Bagley

University of Sussex

UNITED KINGDOM

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Cory Antonio Ocasio

Biological E. Limited

UNITED KINGDOM

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José J. G. Moura

Universidade de Aveiro

PORTUGAL

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Klas Wiman

Karolinska Institutet

SWEDEN

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Luisa Maia

Universidade Nova de Lisboa

PORTUGAL

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Fabio Caradonna

Professore associato

Università degli Studi di Palermo

ITALY

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Thomas Hanke

Goethe University Frankfurt

GERMANY

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Pierre Hainaut

Professor, Cancer Biology. Director, IAB

Université Grenoble Alpes

FRANCE

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Daniel Pinkas

Profesor Titular (Associate Professor)

Universidad Loyola Andalucía

SPAIN

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Graham Langley

University of Southampton

UNITED KINGDOM

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John Spencer

Professor of Bioorganic Chemistry

University of Sussex

UNITED KINGDOM

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Kristian Strømgaard

Københavns Universitet

DENMARK

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Andreas Joerger

Research Interests

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Articles (16)

Development of Potent Dual BET/HDAC Inhibitors via Pharmacophore Merging and Structure-Guided Optimization

Back-Pocket Optimization of 2-Aminopyrimidine-Based Macrocycles Leads to Potent EPHA2/GAK Kinase Inhibitors

Structural basis of p53 inactivation by cavity-creating cancer mutations and its implications for the development of mutant p53 reactivators

Development of Selective Pyrido[2,3-<i>d</i>]pyrimidin-7(8<i>H</i>)-one-Based Mammalian STE20-Like (MST3/4) Kinase Inhibitors.

Structural insights into a regulatory mechanism of FIR RRM1–FUSE interaction

Development of a Potent Cyclic Peptide Inhibitor of the nNOS/PSD-95 Interaction

Structure–Reactivity Studies of 2-Sulfonylpyrimidines Allow Selective Protein Arylation

Synthesis of Pyrazole-Based Macrocycles Leads to a Highly Selective Inhibitor for MST3

From cultivation to cancer: formation of <i>N</i>-nitrosamines and other carcinogens in smokeless tobacco and their mutagenic implications.

Discovery of Nanomolar-Affinity Pharmacological Chaperones Stabilizing the Oncogenic p53 Mutant Y220C

Evolutionary history of the p53 family DNA-binding domain: insights from an Alvinella pompejana homolog

Genotoxicity and Epigenotoxicity of Carbazole-Derived Molecules on MCF-7 Breast Cancer Cells

Development of a Selective Dual Discoidin Domain Receptor (DDR)/p38 Kinase Chemical Probe

Structure-Based Design of Selective Salt-Inducible Kinase Inhibitors

Exploiting vulnerabilities of SWI/SNF chromatin remodelling complexes for cancer therapy

Integrated analysis of Shank1 PDZ interactions with C-terminal and internal binding motifs

Collaborators (13)

Stefan Knapp

Mark Bagley

Cory Antonio Ocasio

José J. G. Moura

Klas Wiman

Luisa Maia

Fabio Caradonna

Thomas Hanke

Pierre Hainaut

Daniel Pinkas

Graham Langley

John Spencer

Kristian Strømgaard

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