Klas Wiman

Karolinska Institutet

Sweden

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Professors in Sweden Professors in Cancer Biology Cancer Biology professors in Sweden

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Articles (10)

Year:

2024

Year:

2024

Year:

2024

Year:

2023

Year:

2023

Year:

2023

Year:

2022

Year:

2022

Year:

2022

Year:

2021

Collaborators (8)

julie bianchi

Karolinska Institutet

SWEDEN

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Tamoghna Mandal

Karolinska Institutet

SWEDEN

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Si Min Zhang

Karolinska Institutet

SWEDEN

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Birthe Meineke

Karolinska Institutet

SWEDEN

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Sean Rudd

Assistant Professor

Karolinska Institutet

SWEDEN

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Vladimir Nakade Bykov

Karolinska Institutet

SWEDEN

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Andreas Joerger

Goethe University Frankfurt

GERMANY

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Amos Tuval

Karolinska Institutet

SWEDEN

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Klas Wiman

Research Interests

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Articles (10)

Pharmacological reactivation of p53 in the era of precision anticancer medicine

Proteome-wide CETSA reveals diverse apoptosis-inducing mechanisms converging on an initial apoptosis effector stage at the nuclear periphery.

Therapeutic targeting of TP53 nonsense mutations in cancer

Novel compounds that synergize with aminoglycoside G418 or eRF3 degraders for translational readthrough of nonsense mutant TP53 and PTEN

Pharmacological induction of translational readthrough of nonsense mutations in the retinoblastoma (RB1) gene

Correction to: Wig-1 regulates cell cycle arrest and cell death through the p53 targets FAS and 14-3-3s.

Correction: Mutant p53-reactivating compound APR-246 synergizes with asparaginase in inducing growth suppression in acute lymphoblastic leukemia cells

Translational readthrough of nonsense mutant TP53 by mRNA incorporation of 5-Fluorouridine.

Evolutionary history of the p53 family DNA-binding domain: insights from an Alvinella pompejana homolog

Mutant p53-reactivating compound APR-246 synergizes with asparaginase in inducing growth suppression in acute lymphoblastic leukemia cells

Collaborators (8)

julie bianchi

Tamoghna Mandal

Si Min Zhang

Birthe Meineke

Sean Rudd

Vladimir Nakade Bykov

Andreas Joerger

Amos Tuval

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