Mats Karlsson

Professor

Uppsala University

Sweden

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Articles (20)

Item performance of the scale for the assessment and rating of ataxia in rare and ultra‐rare genetic ataxias

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Year:

2024

Covariate modeling in pharmacometrics: General points for consideration

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Year:

2024

Predicting the Long‐Term Effects of Therapeutic Neutralization of Oncostatin M on Human Hematopoiesis

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Year:

2024

Quantitative Comparisons of Progressive Supranuclear Palsy Rating Scale Versions Using Item Response Theory

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Year:

2024

Evaluation of model‐integrated evidence approaches for pharmacokinetic bioequivalence studies using model averaging methods

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Year:

2024

Development and comparison of model‐integrated evidence approaches for bioequivalence studies with pharmacokinetic end points

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Year:

2024

Evaluation of covariate effects in item response theory models

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Year:

2024

Item response theory analysis of daytime sleepiness as a symptom of obstructive sleep apnea

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Year:

2024

Properties of the full random‐effect modeling approach with missing covariate data

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Year:

2024

Comparison of Two Methods for Determining Item Characteristic Functions and Latent Variable Time-Course for Pharmacometric Item Response Models

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Year:

2024

Evaluation of the Effect of Erenumab on Migraine‐Specific Questionnaire in Patients with Chronic and Episodic Migraine.

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Year:

2023

Assessment of ibrutinib scheduling on leukocyte, lymph node size and blood pressure dynamics in chronic lymphocytic leukemia through pharmacokinetic‐pharmacodynamic models

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Year:

2023

A multistate modeling and simulation framework to learn dose–response of oncology drugs: Application to bintrafusp alfa in non‐small cell lung cancer

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Year:

2023

Relationship between factor VIII levels and bleeding for rFVIII‐SingleChain in severe hemophilia A: A repeated time‐to‐event analysis

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Year:

2023

Multistate Pharmacometric Model to Define the Impact of Second‐Line Immunotherapies on the Survival Outcome of the IMpower131 Study

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Year:

2023

Comparison of Seven Non-Linear Mixed Effect Model-Based Approaches to Test for Treatment Effect

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Year:

2023

Assessing Prolongation of the Corrected QT Interval with Bedaquiline and Delamanid Coadministration to Predict the Cardiac Safety of Simplified Dosing Regimens

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Year:

2022

Improved Confidence in a Confirmatory Stage by Application of Item-Based Pharmacometrics Model: Illustration with a Phase III Active Comparator-Controlled Trial in COPD Patients

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Year:

2022

Detecting placebo and drug effects on Parkinson's disease symptoms by longitudinal item‐score models

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Year:

2021

Comparison of covariate selection methods with correlated covariates: prior information versus data information, or a mixture of both?

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Year:

2020

Collaborators (7)

Andrew Hooker

Professor of Pharmacometrics

Uppsala University

SWEDEN

Nick Holford

University of Auckland

NEW ZEALAND

Maria Kjellsson

Professor

Uppsala University

SWEDEN

Matthis Synofzik

Professor

Hertie Institute for clinical brain research

GERMANY

Martin Posch

AUSTRIA

Laura Bukkems

Leiden University Medical Center

NETHERLANDS

Lena Friberg

Professor

Uppsala University

SWEDEN

Mats Karlsson

Research Interests

Explore related searches

Contact this professor

Articles (20)

Item performance of the scale for the assessment and rating of ataxia in rare and ultra‐rare genetic ataxias

Covariate modeling in pharmacometrics: General points for consideration

Predicting the Long‐Term Effects of Therapeutic Neutralization of Oncostatin M on Human Hematopoiesis

Quantitative Comparisons of Progressive Supranuclear Palsy Rating Scale Versions Using Item Response Theory

Evaluation of model‐integrated evidence approaches for pharmacokinetic bioequivalence studies using model averaging methods

Development and comparison of model‐integrated evidence approaches for bioequivalence studies with pharmacokinetic end points

Evaluation of covariate effects in item response theory models

Item response theory analysis of daytime sleepiness as a symptom of obstructive sleep apnea

Properties of the full random‐effect modeling approach with missing covariate data

Comparison of Two Methods for Determining Item Characteristic Functions and Latent Variable Time-Course for Pharmacometric Item Response Models

Evaluation of the Effect of Erenumab on Migraine‐Specific Questionnaire in Patients with Chronic and Episodic Migraine.

Assessment of ibrutinib scheduling on leukocyte, lymph node size and blood pressure dynamics in chronic lymphocytic leukemia through pharmacokinetic‐pharmacodynamic models

A multistate modeling and simulation framework to learn dose–response of oncology drugs: Application to bintrafusp alfa in non‐small cell lung cancer

Relationship between factor VIII levels and bleeding for rFVIII‐SingleChain in severe hemophilia A: A repeated time‐to‐event analysis

Multistate Pharmacometric Model to Define the Impact of Second‐Line Immunotherapies on the Survival Outcome of the IMpower131 Study

Comparison of Seven Non-Linear Mixed Effect Model-Based Approaches to Test for Treatment Effect

Assessing Prolongation of the Corrected QT Interval with Bedaquiline and Delamanid Coadministration to Predict the Cardiac Safety of Simplified Dosing Regimens

Improved Confidence in a Confirmatory Stage by Application of Item-Based Pharmacometrics Model: Illustration with a Phase III Active Comparator-Controlled Trial in COPD Patients

Detecting placebo and drug effects on Parkinson's disease symptoms by longitudinal item‐score models

Comparison of covariate selection methods with correlated covariates: prior information versus data information, or a mixture of both?

Collaborators (7)

Andrew Hooker

Nick Holford

Maria Kjellsson

Matthis Synofzik

Martin Posch

Laura Bukkems

Lena Friberg

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