Andrés Olivares-Morales

Sr. Director Head of Immunology and Neurosciences PK/PD

GlaxoSmithKline (United States)

United States

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Andrés Olivares-Morales is the Sr. Director Head of Immunology and Neurosciences PK/PD at Eli Lilly in the United States. His research primarily focuses on the application of physiologically based pharmacokinetic (PBPK) modeling, utilizing machine learning techniques to enhance drug disposition predictions. Recent publications reflect his expertise in predicting pharmacokinetics of highly lipophilic compounds and the translation of pharmacology models to optimize therapeutic benefits.

Articles (10)

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2020

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2020

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2020

Collaborators (3)

Kayode Ogungbenro

Lecturer

The University of Manchester

UNITED KINGDOM

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Gerhard Ecker

University Professor

Universität Wien

AUSTRIA

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Leon Aarons

The University of Manchester

UNITED KINGDOM

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Andrés Olivares-Morales

Research Interests

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Articles (10)

A “middle‐out approach” for the prediction of human drug disposition from preclinical data using simplified physiologically based pharmacokinetic (PBPK) models

A Machine Learning Framework to Improve Rat Clearance Predictions and Inform Physiologically Based Pharmacokinetic Modeling

Investigation of simplified physiologically‐based pharmacokinetic models in rat and human

Evaluation of the Success of High-Throughput Physiologically Based Pharmacokinetic (HT-PBPK) Modeling Predictions to Inform Early Drug Discovery

Can We Predict Clinical Pharmacokinetics of Highly Lipophilic Compounds by Integration of Machine Learning or In Vitro Data into Physiologically Based Models? A Feasibility Study Based on 12 Development Compounds

LipMetE (Lipophilic Metabolism Efficiency) as a Simple Guide for Half-Life and Dosing Regimen Prediction of Oral Drugs

Translating pharmacology models effectively to predict therapeutic benefit.

Correction to: Use of Physiologically Based Pharmacokinetic (PBPK) Modeling for Predicting Drug-Food Interactions: an Industry Perspective.

Use of Physiologically Based Pharmacokinetic (PBPK) Modeling for Predicting Drug-Food Interactions: an Industry Perspective.

Global Sensitivity Analysis of the Rodgers and Rowland Model for Prediction of Tissue: Plasma Partitioning Coefficients: Assessment of the Key Physiological and Physicochemical Factors That Determine Small-Molecule Tissue Distribution

Collaborators (3)

Kayode Ogungbenro

Gerhard Ecker

Leon Aarons

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