Leon Aarons

The University of Manchester

United Kingdom

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Articles (10)

Year:

2025

Year:

2024

Year:

2024

Year:

2023

Year:

2023

Year:

2023

Year:

2023

Year:

2023

Year:

2023

Year:

2022

Collaborators (5)

Hitesh Mistry

The University of Manchester

UNITED KINGDOM

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Paula Chanfreut Palacio

Eindhoven University of Technology

NETHERLANDS

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Kayode Ogungbenro

Lecturer

The University of Manchester

UNITED KINGDOM

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Eva María del Amo Páez

Docent (adjunct professor)

University of Eastern Finland

FINLAND

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Andrés Olivares-Morales

Sr. Director Head of Immunology and Neurosciences PK/PD

GlaxoSmithKline (United States)

UNITED STATES

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Leon Aarons

Research Interests

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Articles (10)

Simultaneous Estimation of fm and FG Values Directly from Clinical Drug-Drug Interaction Study Data

Hierarchical cluster analysis and nonlinear mixed-effects modelling for candidate biomarker detection in preclinical models of cancer.

Constrained numerical deconvolution using orthogonal polynomials

Mixed effects modeling of radiotherapy in combination with immune checkpoint blockade or inhibitors of the DNA damage response pathway

Towards a population pharmacokinetic/pharmacodynamic model of anti-VEGF therapy in patients with age-related macular degeneration

Estimation of FMO3 Ontogeny by Mechanistic Population Pharmacokinetic Modelling of Risdiplam and Its Impact on Drug–Drug Interactions in Children

A “middle‐out approach” for the prediction of human drug disposition from preclinical data using simplified physiologically based pharmacokinetic (PBPK) models

Radiation in Combination with Immune Checkpoint Blockade and DNA Damage Response Inhibitors in Mice

Investigation of simplified physiologically‐based pharmacokinetic models in rat and human

Evaluation of area under the concentration curve adjusted by the terminal‐phase as a metric to reduce the impact of variability in bioequivalence testing

Collaborators (5)

Hitesh Mistry

Paula Chanfreut Palacio

Kayode Ogungbenro

Eva María del Amo Páez

Andrés Olivares-Morales

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