Kayode Ogungbenro

Lecturer

The University of Manchester

United Kingdom

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Kayode Ogungbenro is a Lecturer at The University of Manchester, UK. His research focuses on mathematical modeling and pharmacokinetics, particularly in neuroinflammation, drug delivery, and biomarker detection. Recent publications include studies on population pharmacokinetic modeling and the integration of physiological information into drug efficacy assessments. He is dedicated to advancing precision dosing in clinical practice and improving therapeutic outcomes for patients.

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2025

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2022

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Andrés Olivares-Morales

Sr. Director Head of Immunology and Neurosciences PK/PD

GlaxoSmithKline (United States)

UNITED STATES

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Leon Aarons

The University of Manchester

UNITED KINGDOM

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Kayode Ogungbenro

Research Interests

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About

Articles (20)

Mathematical Modeling of Neuroinflammation in Neurodegenerative Diseases

Population Pharmacokinetic Modeling of Glycochenodeoxycholic Acid 3‐O‐Sulfate (GCDCA‐S) as Endogenous Biomarker of OATP1B3 and OAT3 Transporters

Challenges and Opportunities for Incorporating Physiological Information into Pharmacokinetic Models of Intranasal Drug Delivery to the Brain

Transporter expressions as part of required scaling factor to support in vitro in vivo extrapolation for blood-brain barrier drug permeability

Simultaneous Estimation of fm and FG Values Directly from Clinical Drug-Drug Interaction Study Data

Recommended approaches for integration of population pharmacokinetic modelling with precision dosing in clinical practice

Population Pharmacokinetic Analysis and Simulation of Alternative Dosing Regimens for Biosimilars to Adalimumab and Etanercept in Patients with Rheumatoid Arthritis

Hierarchical cluster analysis and nonlinear mixed-effects modelling for candidate biomarker detection in preclinical models of cancer.

Mixed effects modeling of radiotherapy in combination with immune checkpoint blockade or inhibitors of the DNA damage response pathway

Estimation of FMO3 Ontogeny by Mechanistic Population Pharmacokinetic Modelling of Risdiplam and Its Impact on Drug–Drug Interactions in Children

A “middle‐out approach” for the prediction of human drug disposition from preclinical data using simplified physiologically based pharmacokinetic (PBPK) models

Use of In Vivo Imaging and Physiologically-Based Kinetic Modelling to Predict Hepatic Transporter Mediated Drug–Drug Interactions in Rats

Covariates in population pharmacokinetic studies of critically ill adults receiving β-lactam antimicrobials: a systematic review and narrative synthesis

Exploring the boundaries for in vitro-in vivo extrapolation

Radiation in Combination with Immune Checkpoint Blockade and DNA Damage Response Inhibitors in Mice

Development of a sensitive biochemical assay for the detection of tofacitinib adherence

In Vitro to In Vivo Extrapolation Linked to Physiologically Based Pharmacokinetic Models for Assessing the Brain Drug Disposition

Coproporphyrin I as an endogenous biomarker to detect reduced OATP1B activity and shift in elimination route in chronic kidney disease

Evaluation of area under the concentration curve adjusted by the terminal‐phase as a metric to reduce the impact of variability in bioequivalence testing

Dose individualisation in oncology using chemotherapy‐induced neutropenia: Example of docetaxel in non‐small cell lung cancer patients

Collaborators (13)

Richard Unwin

Alexander G Mathioudakis

Hitesh Mistry

John C. Waterton

Nisha Nair

Sian Bladon

James Bluett

Aleksandra Galetin

Zubida M. Al-Majdoub

Daniel Scotcher

Steven P. Sourbron

Andrés Olivares-Morales

Leon Aarons

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