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Andrzej Rapak

Associate professor

Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences

Poland

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Research Interests

Pharmacology

60%

Pharmaceutical Chemistry

20%

Antioxidant Activity

40%

Radiochemistry

20%

Apoptosis

20%

Flavonoids

20%

Canine Medicine

20%

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Articles14

Proteolytic Activity Inhibition in Gingival Fluid by Cysteine Protease Inhibitors Obtained from Egg White and Fallopia japonica Extract: An In Vitro Study

Article Link

Year:

2025

Functionalized Boron Carbide Nanoparticles as Active Boron Delivery Agents Dedicated to Boron Neutron Capture Therapy.

Article Link

Year:

2025

Cornelian Cherry (Cornus mas L.) Fruit Extract Lowers SREBP-1c and C/EBPα in Liver and Alters Various PPAR-α, PPAR-γ, LXR-α Target Genes in Cholesterol-Rich Diet Rabbit Model

Article Link

Year:

2024

Combustion Synthesis of Functionalized Carbonated Boron Nitride Nanoparticles and Their Potential Application in Boron Neutron Capture Therapy

Article Link

Year:

2024

The Effect of Xanthohumol Derivatives on Apoptosis Induction in Canine Lymphoma and Leukemia Cell Lines

Article Link

Year:

2023

Studies on the Anticancer and Antioxidant Activities of Resveratrol and Long-Chain Fatty Acid Esters

Article Link

Year:

2023

Flowers and Leaves Extracts of Stachys palustris L. Exhibit Stronger Anti-Proliferative, Antioxidant, Anti-Diabetic, and Anti-Obesity Potencies than Stems and Roots Due to More Phenolic Compounds as Revealed by UPLC-PDA-ESI-TQD-MS/MS

Article Link

Year:

2022

Use of natural cysteine protease inhibitors in limiting SARS-Co-2 fusion into human respiratory cells.

Article Link

Year:

2022

Boron-rich boron carbide nanoparticles as a carrier in boron neutron capture therapy: Their influence on tumor and immune phagocytic cells

Article Link

Year:

2021

A newly established canine NK-type cell line and its cytotoxic properties.

Article Link

Year:

2021

Cornelian cherry (Cornus mas L.) iridoid and anthocyanin extract enhances PPAR-α, PPAR-γ expression and reduces I/M ratio in aorta, increases LXR-α expression and alters adipokines and triglycerides levels in cholesterol-rich diet rabbit model

Article Link

Year:

2021

Ubiquitin‐specific protease 7 as a potential therapeutic target in dogs with hematopoietic malignancies

Article Link

Year:

2021

Profile and Content of Phenolic Compounds in Leaves, Flowers, Roots, and Stalks of Sanguisorba officinalis L. Determined with the LC-DAD-ESI-QTOF-MS/MS Analysis and Their In Vitro Antioxidant, Antidiabetic, Antiproliferative Potency

Article Link

Year:

2020

Hypoxia increases the apoptotic response to betulinic acid and betulin in human non-small cell lung cancer cells.

Article Link

Year:

2020

Collaborators25

Elżbieta Pajtasz-Piasecka

Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences

POLAND

Ewa Huszcza

Wroclaw University of Environmental and Life Sciences

POLAND

Sabina Lachowicz-Wiśniewska

Assistant Professor/Doctor

Calisia University

POLAND

Stanisław Cudziło

Military University of Technology in Warsaw

POLAND

Agnieszka Szczygieł

Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences

POLAND

Rodrigo Ledesma-Amaro

Imperial College London

UNITED KINGDOM

Jarosław Popłoński

Assistant profesor

Wroclaw University of Environmental and Life Sciences

POLAND

Veronique A.J. Smits

Profesor asociado para programas de doctorado

Universidad Fernando Pessoa Canarias

SPAIN

Janusz Boratynski

Ludwik Hirszfeld Institute of Immunology and Experimental Therapy

POLAND

Beata Nowak

Wroclaw Medical University

POLAND

Dawid Kozień

AGH University of Science and Technology

POLAND

Renata Samulak

Pomeranian Medical University

POLAND

Bożena Szermer-Olearnik

Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences

POLAND

Mateusz Gratzke

Assistant Professor

Military University of Technology in Warsaw

POLAND

Tomasz Sozański

Wroclaw Medical University

POLAND

Leon Strzadala

Professor, Head of Departament

Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences

POLAND

Zbigniew Pędzich

AGH University of Krakow

POLAND

Zbigniew Lazar

Associate Professor

Wroclaw University of Environmental and Life Sciences

POLAND

Agnieszka Gomułkiewicz

Wroclaw Medical University

POLAND

Anna Gliszczyńska

Wroclaw University of Environmental and Life Sciences

POLAND

Natalia Anger-Góra

Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences

POLAND

Aleksandra Pawlak

Wroclaw University of Environmental and Life Sciences

POLAND

Wioletta Żukiewicz-Sobczak

Prof. associate

Calisia University

POLAND

Ireneusz Ochmian

West Pomeranian University of Technology

POLAND

Sławomir Dyjak

Military University of Technology in Warsaw

POLAND

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Andrzej Rapak

Associate professor

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Research Interests

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Articles14

Proteolytic Activity Inhibition in Gingival Fluid by Cysteine Protease Inhibitors Obtained from Egg White and Fallopia japonica Extract: An In Vitro Study

Functionalized Boron Carbide Nanoparticles as Active Boron Delivery Agents Dedicated to Boron Neutron Capture Therapy.

Cornelian Cherry (<i>Cornus mas</i> L.) Fruit Extract Lowers SREBP-1c and C/EBPα in Liver and Alters Various PPAR-α, PPAR-γ, LXR-α Target Genes in Cholesterol-Rich Diet Rabbit Model

Combustion Synthesis of Functionalized Carbonated Boron Nitride Nanoparticles and Their Potential Application in Boron Neutron Capture Therapy

The Effect of Xanthohumol Derivatives on Apoptosis Induction in Canine Lymphoma and Leukemia Cell Lines

Studies on the Anticancer and Antioxidant Activities of Resveratrol and Long-Chain Fatty Acid Esters

Flowers and Leaves Extracts of <i>Stachys palustris</i> L. Exhibit Stronger Anti-Proliferative, Antioxidant, Anti-Diabetic, and Anti-Obesity Potencies than Stems and Roots Due to More Phenolic Compounds as Revealed by UPLC-PDA-ESI-TQD-MS/MS

Use of natural cysteine protease inhibitors in limiting SARS-Co-2 fusion into human respiratory cells.

Boron-rich boron carbide nanoparticles as a carrier in boron neutron capture therapy: Their influence on tumor and immune phagocytic cells

A newly established canine NK-type cell line and its cytotoxic properties.

Cornelian cherry (Cornus mas L.) iridoid and anthocyanin extract enhances PPAR-α, PPAR-γ expression and reduces I/M ratio in aorta, increases LXR-α expression and alters adipokines and triglycerides levels in cholesterol-rich diet rabbit model

Ubiquitin‐specific protease 7 as a potential therapeutic target in dogs with hematopoietic malignancies

Profile and Content of Phenolic Compounds in Leaves, Flowers, Roots, and Stalks of <i>Sanguisorba officinalis</i> L. Determined with the LC-DAD-ESI-QTOF-MS/MS Analysis and Their In Vitro Antioxidant, Antidiabetic, Antiproliferative Potency

Hypoxia increases the apoptotic response to betulinic acid and betulin in human non-small cell lung cancer cells.

Collaborators25

Elżbieta Pajtasz-Piasecka

Ewa Huszcza

Sabina Lachowicz-Wiśniewska

Stanisław Cudziło

Agnieszka Szczygieł

Rodrigo Ledesma-Amaro

Jarosław Popłoński

Veronique A.J. Smits

Janusz Boratynski

Beata Nowak

Dawid Kozień

Renata Samulak

Bożena Szermer-Olearnik

Mateusz Gratzke

Tomasz Sozański

Leon Strzadala

Zbigniew Pędzich

Zbigniew Lazar

Agnieszka Gomułkiewicz

Anna Gliszczyńska

Natalia Anger-Góra

Aleksandra Pawlak

Wioletta Żukiewicz-Sobczak

Ireneusz Ochmian

Sławomir Dyjak

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