Anthony Dorling

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King’s College London

United Kingdom

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Recent Grants

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Dorling, Manipulating human fibroctes

Open Date: 2016-06-01

Close Date: 2018-02-28

Grant: Close

Paclitaxel assisted balloon Angioplasty of Venous stenosis in haEmodialysis access: The PAVE Trial. A multicentre double-blind randomised controlled trial in haemodialysis patients with a stenosis in a native arteriovenous fistula.

Open Date: 2015-05-01

Close Date: 2019-04-30

Grant: Close

Development of a cytotopically-modified antithrombotic agent for prevention of acute intra-graft thrombosis in transplantation

Open Date: 2013-04-30

Close Date: 2018-05-01

Grant: Close

Development of a cytotopically-modified antithrombotic agent for prevention of acute intra-graft thrombosis in transplantation

Open Date: 2013-04-30

Close Date: 2018-05-01

Grant: Close

Optimized TracrolimuS and MMF for HLA Antibodies after Renal Transplantation (the OuTSMART study): a randomized controlled clinical trial to determine if a combined screening/treatment programme can prevent premature failure of renal transplants due to chronic rejection in patients with HLA antibodies

Open Date: 2013-04-01

Close Date: 2020-09-01

Articles (15)

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King’s College London

UNITED KINGDOM

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Alberto Sanchez-Fueyo

King’s College London

UNITED KINGDOM

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Anthony Dorling

Research Interests

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Recent Grants

Articles (15)

Granulomatous Tubulointerstitial Nephritis in a Kidney Allograft: Treatment with Interleukin-6 Receptor Antagonist Stabilises Kidney Function

Optimized immunosuppression to prevent graft failure in renal transplant recipients with HLA antibodies (OuTSMART): a randomised controlled trial

Can regulatory T cells improve outcomes of sensitised patients after HLA-Ab incompatible renal transplantation: study protocol for the Phase IIa GAMECHANgER-1 trial

The Clinical Utility of Post-Transplant Monitoring of Donor-Specific Antibodies in Stable Renal Transplant Recipients

Inhibition of thrombin on endothelium enhances recruitment of regulatory T cells during IRI and when combined with adoptive Treg transfer, significantly protects against acute tissue injury and prolongs allograft survival

Highly sensitised individuals present a distinct Treg signature compared to unsensitised individuals on haemodialysis

Preventing kidney transplant failure by screening for antibodies against human leucocyte antigens followed by optimised immunosuppression: OuTSMART RCT

Update on the ethical, legal and technical challenges of translating xenotransplantation

A transitional B-cell cytokine biomarker for risk stratifying renal transplant patients with borderline rejection

The phenotype of HLA-binding B cells from sensitized kidney transplant recipients correlates with clinically prognostic patterns of interferon-γ production against purified HLA proteins

Modelling acute antibody-mediated rejection of human kidney transplants using ex-vivo warm machine perfusion.

Manipulation of Tissue Factor-mediated basal PAR-2 signalling on macrophages determines sensitivity for IFNγ responsiveness and significantly modifies the phenotype of murine DTH.

Regulation of T &B cell interactions determines the clinical phenotype associated with donor-specific antibodies

Paclitaxel-assisted balloon angioplasty of venous stenosis in haemodialysis access

Effect of delayed graft function on longer-term outcomes after kidney transplantation from donation after circulatory death donors in the United Kingdom

Collaborators (11)

Abdel Douiri

Sapna shah

Paul McCrone

David Game

Timothy Tree

Jo Spencer

Narayan Karunanithy

Michael G. Robson

Chris Callaghan

Dominic Stringer

Alberto Sanchez-Fueyo

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