Anthony Green

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David Phillips Research Fellow and Lecturer in Organic Chemistry/Chemical Biology

The University of Manchester

United Kingdom

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Anthony Green is a David Phillips Research Fellow and Lecturer in Organic Chemistry and Chemical Biology at the University of Manchester, UK. His research focuses on enzyme design and biocatalysis, with recent articles highlighting topics such as photosensitizer repositioning, enantioselective hydrazone reduction, and the use of noncanonical amino acids in biocatalysis. His work encompasses both theoretical and experimental studies aimed at understanding enzymatic mechanisms and enhancing enzyme functionality.

Recent Grants

Grant: Close

Exploring the Catalytic Properties of Heme Enzymes with Non-Canonical Proximal Ligands

Open Date: 2017-03-01

Close Date: 2019-03-01

Grant: Close

Design and Evolution of Artificial Enzymes with Non-Canonical Organocatalytic Residues

Open Date: 2016-03-30

Close Date: 2021-03-29

Articles (24)

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2022

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2022

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2020

Collaborators (12)

Sven Hennig

University of Amsterdam

NETHERLANDS

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Emma Raven

University of Bristol

UNITED KINGDOM

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David Baker

Professor

University of Washington

UNITED STATES

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Matthew Quesne

Lecturer in Computational Chemistry

University of Leeds

UNITED KINGDOM

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sarah lovelock

The University of Manchester

UNITED KINGDOM

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Colin Levy

The University of Manchester

UNITED KINGDOM

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Sam Hay

The University of Manchester

UNITED KINGDOM

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Eelco Ruijter

University of Amsterdam

NETHERLANDS

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Richard Obexer

UNITED KINGDOM

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Igor Larrosa

Professor

The University of Manchester

UNITED KINGDOM

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Derren Heyes

The University of Manchester

UNITED KINGDOM

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Nicholas J. Turner

UNITED KINGDOM

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Anthony Green

Research Interests

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About

Recent Grants

Articles (24)

Directed Evolution’s Selective Use of Quantum Tunneling in Designed Enzymes─A Combined Theoretical and Experimental Study

Photosensitizer Repositioning Affords an Enantiocomplementary Enzyme for [2 + 2]‐Cycloadditions

­­­Photosensitizer Repositioning Affords an Enantiocomplementary Enzyme for [2+2]‐Cycloadditions

Engineered Biocatalyst for Enantioselective Hydrazone Reduction

Engineered Biocatalyst for Enantioselective Hydrazone Reduction

Engineered enzymes for enantioselective nucleophilic aromatic substitutions

An efficient pyrrolysyl-tRNA synthetase for economical production of MeHis-containing enzymes

Noncanonical Amino Acids in Biocatalysis

Biocatalysis: landmark discoveries and applications in chemical synthesis

Strategies for designing biocatalysts with new functions

A non-canonical nucleophile unlocks a new mechanistic pathway in a designed enzyme

Probing Ferryl Reactivity in a Nonheme Iron Oxygenase Using an Expanded Genetic Code

Mechanistic implications of the ternary complex structural models for the photoenzyme protochlorophyllide oxidoreductase

Multicomponent Synthesis of the SARS-CoV-2 Main Protease Inhibitor Nirmatrelvir

Building Enzymes through Design and Evolution

Design of Heme Enzymes with a Tunable Substrate Binding Pocket Adjacent to an Open Metal Coordination Site

Engineered Biocatalysts for Enantioselective Reductive Aminations of Cyclic Secondary Amines

Engineering enzyme activity using an expanded amino acid alphabet

Engineering Enzymes for Environmental Sustainability

Engineering Enzymes for Environmental Sustainability

A Designed Photoenzyme for Enantioselective [2+2]-Cycloadditions

The road to fully programmable protein catalysis

Engineering an efficient and enantioselective enzyme for the Morita–Baylis–Hillman reaction

Rewiring the ‘Push-Pull’ Catalytic Machinery of a Heme Enzyme using an Expanded Genetic Code

Collaborators (12)

Sven Hennig

Emma Raven

David Baker

Matthew Quesne

sarah lovelock

Colin Levy

Sam Hay

Eelco Ruijter

Richard Obexer

Igor Larrosa

Derren Heyes

Nicholas J. Turner

Make your next move.

Photosensitizer Repositioning Affords an Enantiocomplementary Enzyme for [2+2]‐Cycloadditions