Ashwin Somasundaram

Assistant Professor of Medicine

University of North Carolina at Chapel Hill

United States

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About

Ashwin Somasundaram is an Assistant Professor of Medicine at The University of North Carolina at Chapel Hill, USA. His research areas include immune responses in cancer, T cell dynamics in autoimmune diseases, and the impact of COVID-19 on immune profiles. Recent articles authored by him explore topics such as immune checkpoint blockade, regulatory T cells in cancer outcomes, and predictive immune profiles in critically ill COVID-19 patients.

Articles (9)

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2022

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2021

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2021

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2021

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2021

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2020

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2020

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University of Pittsburgh

UNITED STATES

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Ashwin Somasundaram

Research Interests

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Articles (9)

Fewer LAG-3<sup>+</sup> T Cells in Relapsing-Remitting Multiple Sclerosis and Type 1 Diabetes.

People critically ill with COVID-19 exhibit peripheral immune profiles predictive of mortality and reflective of SARS-CoV-2 lung viral burden.

Intractable Coronavirus Disease 2019 (COVID-19) and Prolonged Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Replication in a Chimeric Antigen Receptor-Modified T-Cell Therapy Recipient: A Case Study

SPaRTAN, a computational framework for linking cell-surface receptors to transcriptional regulators

Prevalence of intratumoral regulatory T cells expressing neuropilin-1 is associated with poorer outcomes in patients with cancer.

Neuropilin-1 is a T cell memory checkpoint limiting long-term antitumor immunity.

Resistance to PD1 blockade in the absence of metalloprotease-mediated LAG3 shedding.

Immune Checkpoint Blockade in Oncogene-Driven Non-Small-Cell Lung Cancer

Systemic immune dysfunction in cancer patients driven by IL6 and IL8 induction of an inhibitory receptor module in peripheral CD8+ T cells

Collaborators (5)

Panayiotis Benos

Mounzer Agha

Harinder Singh

Hatice Osmanbeyoglu

Janet S. Lee

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