Harinder Singh

Professor and Director

University of Pittsburgh

United States

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About

Harinder Singh is a Professor and Director at the University of Pittsburgh, USA. His research focuses on genomic variation, single-cell data integration, and the causal inference of latent factors from multi-omic datasets. Additionally, he investigates the prognostic value of epigenetic alterations in critical illness, as well as the dynamics of cell fate and plasma cell precursors. His recent publications highlight advancements in computational frameworks and methodologies for analyzing cellular mechanisms and immune responses.

Articles (11)

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2024

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2023

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2022

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2022

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2021

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2021

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2021

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2021

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2021

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2021

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2021

Collaborators (16)

Panayiotis Benos

Professor

University of Florida

UNITED STATES

Harinder Singh

Research Interests

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About

Articles (11)

Deciphering the impact of genomic variation on function.

Decision level integration of unimodal and multimodal single cell data with scTriangulate

Essential Regression: A generalizable framework for inferring causal latent factors from multi-omic datasets.

The independent prognostic value of global epigenetic alterations: An analysis of single-cell ATAC-seq of circulating leukocytes from trauma patients followed by validation in whole blood leukocyte transcriptomes across three etiologies of critical illness

SPaRTAN, a computational framework for linking cell-surface receptors to transcriptional regulators

Cell fate dynamics and genomic programming of plasma cell precursors

CISH attenuates homeostatic cytokine signaling to promote lung-specific macrophage programming and function

Coupled analysis of transcriptome and BCR mutations reveals role of OXPHOS in affinity maturation

T-bet+CD27+CD21– B cells poised for plasma cell differentiation during antibody-mediated rejection of kidney transplants

Pseudocell Tracer—A method for inferring dynamic trajectories using scRNAseq and its application to B cells undergoing immunoglobulin class switch recombination

Targeting RNA polymerase II Mediator subunits in cancer therapy

Collaborators (16)

Panayiotis Benos

S. Stephen Yi

richard james

Jishnu Das

Surya Prasath

Hatice Osmanbeyoglu

Yihan Wang

Derek Reiman

Angelo Taglialatela

Jesse Engreitz

Jian Ma

Beatrice Borsari

Ashwin Somasundaram

Yun Li

H. Leighton Grimes

Jasmine Sakr

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