Bastiaan Tops

Head of laboratory for childhood cancer pathology

Prinses Máxima Centrum voor Kinderoncologie

Netherlands

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Dr. Bastiaan Tops is the Head of the Laboratory for Childhood Cancer Pathology at the Prinses Máxima Centrum voor Kinderoncologie in the Netherlands. His research focuses on pediatric oncology, including pharmacogenetics, diagnostic tools for gliomas, and the integration of advanced sequencing techniques in routine diagnostics. Recent publications highlight his work in implementing early pharmacogenetic screening, as well as the molecular characterization of pediatric tumors through innovative methodologies.

Articles (11)

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2025

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2024

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2023

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2023

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2023

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2023

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2023

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2023

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2022

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2022

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2022

Collaborators (10)

Suzanne Baker

Professor

St. Jude Children's Research Hospital

UNITED STATES

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Pieter Wesseling

Amsterdam University Medical Centers

NETHERLANDS

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Monika Hegi

Prof, PhD

Lausanne University Hospital

SWITZERLAND

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Pim French

Assoc Prof

Erasmus MC

NETHERLANDS

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Federico Roncaroli

The University of Manchester

UNITED KINGDOM

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Bjarne Winther Kristensen

Clinical professor (chair)

University of Copenhagen

DENMARK

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Felix Sahm

University Hospital Heidelberg

GERMANY

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Luca Bertero

Associate professor of Pathology

University of Turin

ITALY

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Patrick Kemmeren

Associate Professor

Universitair Medisch Centrum Utrecht

NETHERLANDS

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Jesse Swen

Full professor of clinical pharmacy, in particular translational pharmacogenetics

Leiden University Medical Center

NETHERLANDS

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Bastiaan Tops

Research Interests

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Articles (11)

Implementing Pre‐Emptive Pharmacogenetics: Impact of Early Pharmacogenetic Screening in a Pediatric Oncology Cohort of 1,151 Subjects

RT-PCR assay to detect FGFR3::TACC3 fusions in formalin-fixed, paraffin-embedded glioblastoma samples

Correction to: Amplification of the PLAG-family genes—PLAGL1 and PLAGL2—is a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification (Acta Neuropathologica, (2023), 145, 1, (49-69), 10.1007/s00401-022-02516-2)

Amplification of the PLAG-family genes-PLAGL1 and PLAGL2-is a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification

Molecular diagnostic tools for the World Health Organization (WHO) 2021 classification of gliomas, glioneuronal and neuronal tumors; an EANO guideline

Integration of RNA Sequencing, Whole Exome Sequencing, and Flow Cytometry Into Routine Diagnostic Workup of Pediatric Lymphomas.

Ultra-fast deep-learned CNS tumour classification during surgery.

Systematic discovery of gene fusions in pediatric cancer by integrating RNA-seq and WGS.

Trecode: A FAIR Eco-System for the Analysis and Archiving of Omics Data in a Combined Diagnostic and Research Setting

Genetic variants found in paediatric oncology patients with severe chemotherapy-induced toxicity: A case series.

NTRK rearrangements in a subset of NF1-related malignant peripheral nerve sheath tumors as novel actionable target.

Collaborators (10)

Suzanne Baker

Pieter Wesseling

Monika Hegi

Pim French

Federico Roncaroli

Bjarne Winther Kristensen

Felix Sahm

Luca Bertero

Patrick Kemmeren

Jesse Swen

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