Benoit Viollet
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Recent Grants
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Targeting AMPK for the Control of Intestinal epithelial barrier integrity
Open Date: 2020-01-01
Close Date: 2023-06-01
Grant: Close
Cellular metabolism of Treg in the control of chronic inflammatory diseases
Open Date: 2018-06-01
Close Date: 2021-06-01
Grant: Close
Role of SIK protein kinases in the regulation of hepatic glucose production and therapeutic perspectives for type 2 diabetes
Open Date: 2016-01-01
Close Date: 2019-12-01
Grant: Close
Therapeutic of hepatic metabolic disorders: AMPK activation and control of hepatocyte ploidy
Open Date:
Close Date:
Articles (16)
This study shows that the energy sensor and transducer, AMP-activated protein kinase (AMPK), is necessary for an exercise training-induced: 1) increase in liver glycogen that is necessary for accelerated glycogenolysis during exercise, 2) decrease in liver glycerolipids independent of tricarboxylic acid (TCA) cycle flux, and 3) decline in the desaturation and elongation of fatty acids comprising liver diacylglycerides. The mechanisms defined in these studies have implications for use of regular exercise or AMPK-activators in patients with fatty liver.
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2024
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Collaborators (14)
Ramaroson Andriantsitohaina
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David H. Wasserman
Vanderbilt University
Fadi G. Akar
Associate Professor
Yale University
Colin Palmer
Academic, Professor (Teaching and Research) of Pharmacogenomics
University of Dundee
Craig Beall
Senior Lecturer
University of Exeter
Raid Nisr
University of Dundee
Tommy Lewis
Assistant Member
Oklahoma Medical Research Foundation
Ify Mordi
Academic, Clinical Sen Lecturer/Honorary Cons (Teaching and Research)
University of Dundee
Jerome LEROY
Full Professor
Université Paris-Saclay
NICOLAS DUPONT
Institut Necker-Enfants Malades
Bruno Guigas
Associate Professor
Leiden University Medical Center
Cyril Bourgeois
Co-head of the ReGArDS team
École normale supérieure de Lyon
Graham Rena
Academic, Professor (Teaching and Research) of CARDIOVASCULAR AND METABOLIC MEDICINE
University of Dundee
Kerry McPhail
Professor
Oregon State University College of Pharmacy
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