Binghe Wang

Associate Professor

North Carolina State University

United States

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About

Dr. Binghe Wang is an Associate Professor at North Carolina State University, USA. His research interests encompass biotin-mediated drug delivery, the therapeutic potential of carbon monoxide, and the development of entry inhibitors targeting SARS-CoV-2. His recent publications highlight innovative approaches to drug design and the role of carbon monoxide in therapeutic contexts.

Articles (29)

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Collaborators (6)

Thomas Prisinzano

Professor

University of Kentucky

UNITED STATES

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Xiaoxiao Yang

University of Georgia

UNITED STATES

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Hideaki Kakeya

Professor

Kyoto University

JAPAN

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A. Douglas Kinghorn

Professor and Jack L. Beal Chair

Ohio State University

UNITED STATES

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Rodrigo Wagner Alves de Souza

Assistant Professor of Surgery

Harvard Medical School

UNITED STATES

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Mukesh Kumar

Assistant Professor

University of Georgia

UNITED STATES

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Binghe Wang

Research Interests

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About

Articles (29)

Winners of the 2024 Tu Youyou Award

Carbon monoxide potentiates the effect of corticosteroids in suppressing inflammatory responses in cell culture

Entry Inhibitors of SARS-CoV-2 Targeting the Transmembrane Domain of the Spike Protein

Biotin-mediated drug delivery: does the biotin transporter mediate uptake of biotin conjugates?

Compelling Evidence: A Critical Update on the Therapeutic Potential of Carbon Monoxide

Front Cover Image, Volume 45, Issue 4

Thioether Oxidation Chemistry in Reactive Oxygen Species (ROS)-Sensitive Trigger Design: A Kinetic Analysis

Characterization of the CO release properties of a common CO donor, CORM-401, in the context of its application in studying CO biology

Folate-conjugated organic CO prodrugs: Synthesis and CO release kinetic studies

Reversible in-situ assembly of PROTACs using iminoboronate conjugation

Iron porphyrin-mediated production of carbon monoxide from phenylpyruvic acid: from potential therapeutic and diagnostic use to physiological implications

On the Question of Uncatalyzed CO Insertion into a Hydrazone Double Bond: A Comparative Study Using Different CO Sources and Substrates

Carbon Monoxide as a Potential Therapeutic Agent: A Molecular Analysis of Its Safety Profiles

Quantitative Factors Introduced in the Feasibility Analysis of Reactive Oxygen Species (ROS)‐Sensitive Triggers

Quantitative Factors Introduced in the Feasibility Analysis of Reactive Oxygen Species (ROS)‐Sensitive Triggers

On the Question of CO’s Ability to Induce HO-1 Expression in Cell Culture: A Comparative Study Using Different CO Sources

Unraveling the Interplay of Dopamine, Carbon Monoxide, and Heme Oxygenase in Neuromodulation and Cognition

Metal-Free CO Prodrugs Activated by Molecular Oxygen Protect against Doxorubicin-Induced Cardiomyopathy in Mice

CO prodrugs: a new scaffold of adamantane-fused norbornen-7-ones with tunable water solubility

Sensing a CO-Releasing Molecule (CORM) Does Not Equate to Sensing CO: The Case of DPHP and CORM-3

Click chemistry and drug delivery: A bird's-eye view

Toward “CO in a Pill”: Silica-Immobilized Organic CO Prodrugs for Studying the Feasibility of Systemic Delivery of CO via In Situ Gastrointestinal CO Release

Mutual leveraging of proximity effects and click chemistry in chemical biology

De Novo Construction of Fluorophores via CO Insertion-Initiated Lactamization: A Chemical Strategy toward Highly Sensitive and Highly Selective Turn-On Fluorescent Probes for Carbon Monoxide

Reassessing CORM-A1: redox chemistry and idiosyncratic CO-releasing characteristics of the widely used carbon monoxide donor

Upregulation of p53 through induction of MDM2 degradation: improved potency through the introduction of an alkylketone sidechain on the anthraquinone core

Light-Activated CO Donor as a Universal CO Surrogate for Pd-Catalyzed and Light-Mediated Carbonylation

"CO in a pill": Towards oral delivery of carbon monoxide for therapeutic applications.

Thiouracil SecA inhibitors: bypassing the effects of efflux pumps and attenuating virulence factor secretion in MRSA and Bacillus anthracis

Collaborators (6)

Thomas Prisinzano

Xiaoxiao Yang

Hideaki Kakeya

A. Douglas Kinghorn

Rodrigo Wagner Alves de Souza

Mukesh Kumar

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