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Brian Annex

Professor and Chair

Augusta University Medical College of Georgia

United States

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Research Interests

Cell Biology

30%

Cardiology

50%

Endothelial Function

40%

Inflammatory Biology

40%

Vascular Biology

40%

Angiogenesis

30%

Atherosclerosis

20%

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Articles14

Impact of ligand binding on VEGFR1, VEGFR2, and NRP1 localization in human endothelial cells

Article Link

Year:

2025

Getting to the heart of cardiovascular complications associated with inflammatory arthritis

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Year:

2025

Inhibiting anti-angiogenic VEGF165b activates a miR-17-20a-Calcipressin-3 pathway that revascularizes ischemic muscle in peripheral artery disease

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Year:

2024

Glucosamine-Mediated Hexosamine Biosynthesis Pathway Activation Uses ATF4 to Promote “Exercise-Like” Angiogenesis and Perfusion Recovery in PAD

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Year:

2024

A conundrum of arterialized capillaries and vascular dilation in chronic limb-threatening ischaemia

Article Link

Year:

2024

Pentose Pathway Activation Is Superior to Increased Glycolysis for Therapeutic Angiogenesis in Peripheral Arterial Disease

Article Link

Year:

2023

Experiment-based computational model predicts that IL-6 classic and trans-signaling exhibit similar potency in inducing downstream signaling in endothelial cells

Article Link

Year:

2023

Targeting Anti-Angiogenic VEGF165b–VEGFR1 Signaling Promotes Nitric Oxide Independent Therapeutic Angiogenesis in Preclinical Peripheral Artery Disease Models

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Year:

2022

Machine Learning Approach to Predict In‐Hospital Mortality in Patients Admitted for Peripheral Artery Disease in the United States

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Year:

2022

Elevated Cytokine Levels in Plasma of Patients with SARS-CoV-2 Do Not Contribute to Pulmonary Microvascular Endothelial Permeability

Article Link

Year:

2022

MicroRNA-30b Is Both Necessary and Sufficient for Interleukin-21 Receptor-Mediated Angiogenesis in Experimental Peripheral Arterial Disease

Article Link

Year:

2021

AGGF1 Shows the α5β1 Integrin to Be Another Akt-or in a Common Angiogenesis Scene

Article Link

Year:

2021

New Directions in Therapeutic Angiogenesis and Arteriogenesis in Peripheral Arterial Disease

Article Link

Year:

2021

A data-driven computational model enables integrative and mechanistic characterization of dynamic macrophage polarization

Article Link

Year:

2021

Collaborators9

Aleksander Popel

Professor

Johns Hopkins University

UNITED STATES

Eric J. Belin de Chantemele

Professor

Augusta University Medical College of Georgia

UNITED STATES

Yike Li

Vanderbilt University Medical Center

UNITED STATES

Sarvenaz Sarabipour

Assistant Professor

University of Connecticut Health Center

UNITED STATES

Tohru Fukai

Barbara Schnuck Professor

Augusta University Medical College of Georgia

UNITED STATES

Vijay Ganta

Assistant Professor

Augusta University

UNITED STATES

John Cooke

Professor and Department Chair

Houston Methodist Research Institute

UNITED STATES

Masuko Ushio‐Fukai

UNITED STATES

Donglan Zhang

Associate Professor

New York University Long Island School of Medicine

UNITED STATES

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