Tohru Fukai

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Barbara Schnuck Professor

Augusta University Medical College of Georgia

United States

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About

Tohru Fukai is the Barbara Schnuck Professor at Augusta University Medical College of Georgia. His research focuses on vascular biology, with recent articles exploring topics such as endothelial function, angiogenesis, and the metabolic connections underlying vascular diseases. He has made significant contributions to understanding diabetic complications and therapeutic approaches for peripheral arterial disease.

Recent Grants

Grant: Close

Antioxidant-1 as a mechanosensitive Cu-and ROS- dependent transcription factor in vascular inflammatory disease

Open Date: 2022-07-01

Close Date: 2025-06-30

Articles (10)

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2025

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UNITED STATES

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Brian Annex

Professor and Chair

Augusta University Medical College of Georgia

UNITED STATES

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Reem Atawia

Assistant Professor of Pathophysiology and Pharmacology

Southwestern Oklahoma State University

UNITED STATES

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Thiago Bruder do Nascimento

Assistant Professor

University of Pittsburgh

UNITED STATES

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Tohru Fukai

Research Interests

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About

Recent Grants

Articles (10)

PFKFB3 Connects Glycolytic Metabolism with Endothelial Dysfunction in Human and Rodent Obesity

Splicing factor kinase SRPK1 inhibition in monocyte: a novel therapeutic approach for peripheral arterial disease

Exercise-Induced SOD3/H 2 O 2 Sulfenylates PKG1α to Restore Vasodilation in Diabetes

Pentose Pathway Activation Is Superior to Increased Glycolysis for Therapeutic Angiogenesis in Peripheral Arterial Disease

Type 1 Diabetes Impairs Endothelium-Dependent Relaxation Via Increasing Endothelial Cell Glycolysis Through Advanced Glycation End Products, PFKFB3, and Nox1-Mediated Mechanisms

Whole-Transcriptome Sequencing Analyses of Nuclear Antixoxidant-1 in Endothelial Cells: Role in Inflammation and Atherosclerosis

The P-type ATPase transporter ATP7A promotes angiogenesis by limiting autophagic degradation of VEGFR2

Interplay Between Reactive Oxygen/Reactive Nitrogen Species and Metabolism in Vascular Biology and Disease

Caveolin-1 stabilizes ATP7A, a copper transporter for extracellular SOD, in vascular tissue to maintain endothelial function.

Cross-Talk between NADPH Oxidase and Mitochondria: Role in ROS Signaling and Angiogenesis.

Collaborators (8)

Eric J. Belin de Chantemele

Rudolf Lucas

Vijay Ganta

Seock-Won Youn

Masuko Ushio‐Fukai

Brian Annex

Reem Atawia

Thiago Bruder do Nascimento

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