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Brigitta Loretz

Senior Scientist

Helmholtz Institute for Pharmaceutical Research Saarland

Germany

Research Interests

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Professors in Germany Professors in Biochemistry Biochemistry professors in Germany

Articles (20)

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2026

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2023

Collaborators (11)

Alexander Felix Kiefer

Group Leader

Helmholtz Institute for Pharmaceutical Research Saarland

GERMANY

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Mariia Nesterkina

Helmholtz Institute for Pharmaceutical Research Saarland

GERMANY

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Sangeun Lee

Junior Professor

Saarland University

GERMANY

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Frederik Lermyte

Technische Universität Darmstadt

GERMANY

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Anna Katharina Herta Hirsch

Full professor (W3)

Saarland University

GERMANY

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Nicole Schneider-Daum

Helmholtz Institute for Pharmaceutical Research Saarland

GERMANY

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Mohamed Ashraf Mostafa Kamal

GERMANY

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Claus-Michael Lehr

Professor and Head of Dept

Helmholtz Institute for Pharmaceutical Research Saarland

GERMANY

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Agnes-Valencia Weiss

Saarland University

GERMANY

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Katharina Rox

Helmholtz Centre for Infection Research

GERMANY

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Tobias Kraus

Professor

Saarland University

GERMANY

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Brigitta Loretz

Research Interests

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Articles (20)

A multivalent TAT–arginine-biodynamer conjugate targeting the bacterial cell envelope via specific membrane interactions

Toward Anti‐Herpesviral PROTACs: Assessing the Challenges for Targeted Protein Degradation on the Example of Kaposi's Sarcoma‐Associated Herpesvirus Latency‐Associated Nuclear Antigen

A stretchable human lung‐on‐chip model of alveolar inflammation for evaluating anti‐inflammatory drug response

Tobramycin crosslinking improves the colloidal stability of arginine chitosan biodynamers for safe and efficient siRNA delivery

Soft mist inhaler nebulization by Rayleigh-breakup largely preserves functional integrity of liposomal mRNA in respirable aerosols

Exploring the future of mRNA delivery: Beyond lipid nanoparticles

A novel lipopolyplex platform for dual mRNA delivery via core- and surface-loading

The HIPS 2024 symposium: highlighting advances in pharmaceutical sciences in infection research

Arg-biodynamers as antibiotic potentiators through interacting with Gram-negative outer membrane lipopolysaccharides

Antimicrobial and antibiotic-potentiating effect of calcium peroxide nanoparticles on oral bacterial biofilms

A Novel 3D Printed Model of Infected Human Hair Follicles to Demonstrate Targeted Delivery of Nanoantibiotics

Design and evaluation of nanostructured lipid carrier of Bergenin isolated from Pentaclethra macrophylla for anti-inflammatory effect on lipopolysaccharide-induced inflammatory responses in macrophages

Biodynamer Nano-Complexes and-Emulsions for Peptide and Protein Drug Delivery

Realizing time-staggered expression of nucleic acid-encoded proteins by co-delivery of messenger RNA and plasmid DNA on a single nanocarrier

Targeting Intracellular Bacteria with Dual Drug-loaded Lactoferrin Nanoparticles

Drug solubility in biorelevant media in the context of an inhalation-based biopharmaceutics classification system (iBCS)

pH-Responsive Dynaplexes as Potent Apoptosis Inductors by Intracellular Delivery of Survivin siRNA

Functional Materials to Overcome Bacterial Barriers and Models to Advance Their Development

Anti-Inflammatory and Antinociceptive Activity of Herbal Lipospheres of Pentaclethra macrophylla (Fabaceae) Stem Bark Extract

Inhibitors of the Elastase LasB for the Treatment of <i>Pseudomonas aeruginosa</i> Lung Infections

Collaborators (11)

Alexander Felix Kiefer

Mariia Nesterkina

Sangeun Lee

Frederik Lermyte

Anna Katharina Herta Hirsch

Nicole Schneider-Daum

Mohamed Ashraf Mostafa Kamal

Claus-Michael Lehr

Agnes-Valencia Weiss

Katharina Rox

Tobias Kraus

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