Catherijne A J Knibbe

Leiden University

Netherlands

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Articles (20)

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2025

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2022

Collaborators (17)

Jason Doppenberg

Leiden University Medical Center

NETHERLANDS

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Zhiyuan Tan

Leiden University

NETHERLANDS

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Marc Pfister

SWITZERLAND

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Bart van Hoek

Professor of Hepatology

Leiden University

NETHERLANDS

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Tingjie Guo

Assistant Professor

Leiden University

NETHERLANDS

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Roger J M Brüggemann

Radboud University Medical Center

NETHERLANDS

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Reinier M. van Hest

University of Amsterdam

NETHERLANDS

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J.G.C. van Hasselt

Associate professor

Leiden University

NETHERLANDS

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Elke Krekels

Assistant Professor

Leiden University

NETHERLANDS

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Jean‐Marc Treluyer

FRANCE

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Oana Ciofu

Københavns Universitet

DENMARK

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Sinno Simons

NETHERLANDS

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D. M. Burger

Radboud University Medical Center

NETHERLANDS

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Laura Bertien Zwep

Assistant professor Statistics and Pharmacometrics

Leiden University

NETHERLANDS

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Michiel Schreuder

Professor Pediatric Nephrology

Radboudumc

NETHERLANDS

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Samira Samiee-Zafarghandy

Associate Professor

McMaster University

CANADA

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Catherine Sherwin

Professor and Vice Chair of Research

Wright State University Boonshoft School of Medicine

UNITED STATES

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Catherijne A J Knibbe

Research Interests

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Articles (20)

Patients in Clinical Trials are Sub‐Optimally Protected for Drug–Drug Interactions: A Call for Action

A Systematic Evaluation of the Dosing Regimens for Approved Targeted Therapies and Immune Checkpoint Inhibitors in Metastatic Renal Cell Carcinoma From a Project OPTIMUS Perspective

Colistin resistance dynamics in Pseudomonas aeruginosa under biofilm and planktonic growth

The Impact of Drug Properties and Severity of Obesity on Renal Drug Clearance Through Glomerular Filtration and Active Tubular Secretion: A Systematic Analysis Using PBPK Modeling

All You Need to Know About Allometric Scaling: An Integrative Review on the Theoretical Basis, Empirical Evidence, and Application in Human Pharmacology

Virtual Patient Simulation Using Copula Modeling

Changes in Plasma Clearance of CYP450 Probe Drugs May Not be Specific for Altered In Vivo Enzyme Activity Under (Patho)Physiological Conditions: How to Interpret Findings of Probe Cocktail Studies

Impact of Obesity on Hepatic Drug Clearance: What are the Influential Variables?

Patients with obesity should be recognised as a special patient population during drug development of antibacterial and antifungal agents

How to Dose Vancomycin in Overweight and Obese Patients with Varying Renal (Dys)function in the Novel Era of AUC 400–600 mg·h/L-Targeted Dosing

Vancomycin Clearance in Obese Adults is not Predictive of Clearance in Obese Adolescents

An Integrated Population Pharmacokinetic Analysis for Posaconazole Oral Suspension, Delayed-Release Tablet, and Intravenous Infusion in Healthy Volunteers

Novel Explanted Human Liver Model to Assess Hepatic Extraction, Biliary Excretion and Transporter Function

Maturation of Paracetamol Elimination Routes in Preterm Neonates Born Below 32 Weeks of Gestation

Oral Ibuprofen Is More Effective than Intravenous Ibuprofen for Closure of a Patent Ductus Arteriosus: Can Pharmacokinetic Modeling Help Us to Understand Why?

Population pharmacokinetics of intravenous cefotaxime indicates that higher doses are required for critically ill children

Ciprofloxacin Pharmacokinetics After Oral and Intravenous Administration in (Morbidly) Obese and Non-obese Individuals: A Prospective Clinical Study

Total bodyweight and sex both drive pharmacokinetic variability of fluconazole in obese adults

General clinical and methodological considerations on the extrapolation of pharmacokinetics and optimization of study protocols for small molecules and monoclonal antibodies in children

Impact of mucositis on oral bioavailability and systemic exposure of ciprofloxacin Gram-negative infection prophylaxis in patients with haematological malignancies

Collaborators (17)

Jason Doppenberg

Zhiyuan Tan

Marc Pfister

Bart van Hoek

Tingjie Guo

Roger J M Brüggemann

Reinier M. van Hest

J.G.C. van Hasselt

Elke Krekels

Jean‐Marc Treluyer

Oana Ciofu

Sinno Simons

D. M. Burger

Laura Bertien Zwep

Michiel Schreuder

Samira Samiee-Zafarghandy

Catherine Sherwin

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