Christine Beemelmanns

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Professor

Saarland University

Germany

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About

Christine Beemelmanns is a Professor at Saarland University in Germany. Her research focuses on biosynthesis, particularly related to N-acyl tyrosines, polyketides, and the biological significance of bacterial metabolites. Recent articles highlight her work on comparative genomics and the molecular networking of microbiota, contributing to advances in understanding microbial interactions and their therapeutic potential.

Recent Grants

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OMICs based analysis of cytochalasans in fungal-bacteria-insect interactions

Open Date: 2021-01-01

Close Date:

Grant: Close

Deciphering Bacteria-induced Morphogenesis and Protection in marine Eukaryotes

Open Date: 2019-02-01

Close Date: 2024-01-31

Grant: Close

Isolation, Characterization and Functional Analysis of Novel Biomolecules from the Mutualistic Food Fungus and Associated Microbes of Fungus-Growing Termites (A06)

Open Date: 2018-01-01

Close Date:

Grant: Close

Biomimetic synthesis, biosynthetic pathway engineering and structure activities studies of unique glycosolyated macrolactams

Open Date: 2017-01-01

Close Date: 2022-12-31

Grant: Close

Exploitation and total synthesis of new microbial sphingolipid-type signaling molecules (EXSPHINGO)

Open Date: 2016-01-01

Close Date:

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Collaborators (14)

Immo Burkhardt

University of California, San Diego

UNITED STATES

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Knud Jønsson

Københavns Universitet

DENMARK

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Thomas Wichard

Friedrich Schiller University Jena

GERMANY

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Joel Vizueta

Assistant Professor

University of Copenhagen

DENMARK

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Jan Stanstrup

Københavns Universitet

DENMARK

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Jan Wolfgang Schwitalla

Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie eV Hans-Knöll-Institut

GERMANY

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Jan Marienhagen

Professor

RWTH Aachen University

GERMANY

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Christoph Mayer

Prof. Dr.

University of Tübingen

GERMANY

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Jamshid Amiri Moghaddam

GERMANY

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Kasun Bodawatta

Københavns Universitet

DENMARK

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Ivan Vilotijevic

Assistant professor

Friedrich Schiller University Jena

GERMANY

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Michael Poulsen

Københavns Universitet

DENMARK

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Benjamin Conlon

Københavns Universitet

DENMARK

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Thomas Krüger

Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie eV Hans-Knöll-Institut

GERMANY

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Christine Beemelmanns

Research Interests

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About

Recent Grants

Articles (22)

Investigations into the biosynthesis of stieleriacines and related N-acyl tyrosines by comparative genomics, knock-out studies and total synthesis of epi-stieleriacine C

Anti-adipogenic effects of N-acetyltyramine from termite-associated Streptomyces sp. M45

Structures, biosynthetic pathways, and biological significance of bacterial aryl-heterocycle metallophores with emphasis on yersiniabactin-type derivatives

A type III polyketide synthase cluster in the phylum Planctomycetota is involved in alkylresorcinol biosynthesis

Comparative genomics unravels a rich set of biosynthetic gene clusters with distinct evolutionary trajectories across fungal species (Termitomyces) farmed by termites

Structure Revision of Halisphingosine A via Total Synthesis and Bioactivity Studies

Strukturrevision von Halisphingosin A durch Totalsynthese und Bioaktivitätsstudien

Decoding the diagnostic and therapeutic potential of microbiota using pan-body pan-disease microbiomics

Statistical analysis of feature-based molecular networking results from non-targeted metabolomics data

Molecular networking and computational NMR analyses uncover six polyketide-terpene hybrids from termite-associated Xylaria isolates

Synthesis of Aryl‐ and Alkyl‐Containing 3‐Methylene‐5‐hydroxy Esters via a Barbier Allylation Reaction

Adaptations of Pseudoxylaria towards a comb-associated lifestyle in fungus-farming termite colonies

Isolation, (bio)synthetic studies and evaluation of antimicrobial properties of drimenol-type sesquiterpenes of Termitomyces fungi

Multiple mutations in the Nav1.4 sodium channel of New Guinean toxic birds provide autoresistance to deadly batrachotoxin

Isolation of sulfonosphingolipids from the rosette-inducing bacterium Zobellia uliginosa and evaluation of their rosette-inducing activity

Genome mining for macrolactam-encoding gene clusters allowed for the network-guided isolation of β-amino acid-containing cyclic derivatives and heterologous production of ciromicin A

Heterologous expression of the cryptic mdk gene cluster and structural revision of maduralactomycin A

Identification of the new prenyltransferase Ubi-297 from marine bacteria and elucidation of its substrate specificity

Desaturation of the Sphingofungin Polyketide Tail Results in Increased Serine Palmitoyltransferase Inhibition

Total Synthesis and Functional Evaluation of IORs, Sulfonolipid‐based Inhibitors of Cell Differentiation in Salpingoeca rosetta

Insights into the Metabolomic Capacity of Podaxis and Isolation of Podaxisterols A–D, Ergosterol Derivatives Carrying Nitrosyl Cyanide-Derived Modifications

GNPS‐Guided Discovery of Madurastatin Siderophores from the Termite‐Associated Actinomadura sp. RB99**

Collaborators (14)

Immo Burkhardt

Knud Jønsson

Thomas Wichard

Joel Vizueta

Jan Stanstrup

Jan Wolfgang Schwitalla

Jan Marienhagen

Christoph Mayer

Jamshid Amiri Moghaddam

Kasun Bodawatta

Ivan Vilotijevic

Michael Poulsen

Benjamin Conlon

Thomas Krüger

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