Daniel Hyer

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Associate Professor

Iowa State University
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About

Daniel Hyer is an Associate Professor at the University of Iowa, USA. His research interests focus on advanced radiation therapy techniques, medical imaging, and treatment methodologies for cancer, particularly in prostate and melanoma patients. Recent publications include studies on MR-guided radiation therapy and innovative proton therapy approaches. He is dedicated to improving clinical outcomes and prognostication in oncology patients.

Recent Grants

Grant: Close

Optimization and evaluation of new motion monitoring image sequences on the Unity

Open Date: 2022-09-01

Close Date: 2023-08-01

Grant: Close

Usability evaluation and algorithms performance review for the Unity gating solution

Open Date: 2021-05-01

Close Date: 2022-08-01

Grant: Close

Evaluate treatment planning improvements for the Unity System using Research Monaco

Open Date: 2020-11-01

Close Date: 2021-11-01

Grant: Close

Sharpening the edge in pencil-beam proton therapy: an aftermarket collimation system to better spare normal tissue during radiation treatment

Open Date: 2018-09-01

Close Date: 2025-08-01

Grant: Close

Dynamic Collimation System

Open Date: 2014-07-01

Close Date: 2015-11-01

Articles (27)

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2025

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2025

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2025

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2025

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2025

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2025

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2025

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2025

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2025

The Elekta Unity magnetic resonance (MR) linac is limited to longitudinal couch motion and a sagittal‐only laser, which restricts the ability to perform patient‐specific quality assurance (PSQA) intensity‐modulated radiotherapy (IMRT) measurements for very lateral targets. This work introduces a simple method to perform PSQA using the Sun Nuclear ArcCheck‐MR phantom at left and right lateral positions without additional equipment or in‐house construction. The proposed setup places the center of the phantom 1.3 cm vertical and 12.9 cm lateral to isocenter in either the left or right direction. Computed tomography (CT) scans are used to simulate the setup and create a QA plan template in the Monaco treatment planning system (TPS). The workflow is demonstrated for four patients, with an average axial distance from the center of the bore to the planning target volume (PTV) of 12.4 cm. Gamma pass rates were above 94% for all plans using global 3%/2 mm gamma criterion with a 10% threshold. Setup uncertainties are slightly larger for the proposed lateral setup compared to the centered setup on the Elekta platform (∼1 mm compared to ∼0.5 mm), but acceptable pass rates are achievable without optimizing shifts in the gamma analysis software. In general, adding the left and right lateral positions increases the axial area in the bore encompassed by the cylindrical measurement array by 147%, substantially increasing the flexibility of measurements for offset targets. Based on this work, we propose using the lateral QA setup if the closest distance to the PTV edge from isocenter is larger than the array radius (10.5 cm) or the percent of the PTV encompassed by the diode array would be increased with the lateral setup compared to the centered setup.

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2024

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2024

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2024

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2024

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2024

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2023

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2023

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2023

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2023

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2023

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2023

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2022

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2022

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2022

Collaborators (9)

Jui-Kai Wang

Assistant Professor

University of Texas Southwestern Medical Center

UNITED STATES
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John Buatti

Professor and Chair

The University of Iowa

UNITED STATES
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Wesley Culberson

Associate Professor

University of Wisconsin-Madison

UNITED STATES
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Mohammed Milhem

Oncology Section Chief

University of Iowa Healthcare

UNITED STATES
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Margaret Kozak

Assistant Professor

The University of Iowa

UNITED STATES
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Isabella Grumbach

Iowa State University

UNITED STATES
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Martin Fast

Universitair Medisch Centrum Utrecht

NETHERLANDS
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Joel J. St‐Aubin

-

UNITED STATES
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Mona Garvin

Iowa State University

UNITED STATES
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