Isabella Grumbach

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Iowa State University

United States

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Recent Grants

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Laser speckle flowgraphy as early indicator of microvasculopathy in radiation-induced vision loss

Open Date: 2020-05-01

Close Date: 2025-04-30

Grant: Close

New models of radiation endotheliopathy

Open Date: 2018-07-01

Close Date: 2020-06-30

Grant: Close

CaMKII in mitochondria drives smooth muscle migration and neointimal hyperplasia

Open Date: 2017-07-01

Close Date: 2019-06-30

Grant: Close

CaMKII as a regulator of diabetic retinopathy

Open Date: 2015-01-01

Close Date: 2017-09-30

Grant: Close

Mitochondrial CaMKII drives smooth muscle migration and neointimal hyperplasia

Open Date: 2012-04-16

Close Date: 2021-11-30

Articles (18)

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Collaborators (13)

Bradley McDowell

The University of Iowa

UNITED STATES

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Jui-Kai Wang

Assistant Professor

University of Texas Southwestern Medical Center

UNITED STATES

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Ryan Boudreau

Associate Professor

The University of Iowa

UNITED STATES

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Florida State University

UNITED STATES

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Daniel Hyer

Associate Professor

Iowa State University

UNITED STATES

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Jared McLendon

Assistant Professor

The University of Iowa

UNITED STATES

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Sakthivel Sadayappan

Professor

University of Cincinnati

UNITED STATES

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Mona Garvin

Iowa State University

UNITED STATES

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Isabella Grumbach

Research Interests

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Recent Grants

Articles (18)

Avasopasem Manganese Shows Potential to Reduce High‐Risk Carotid Plaque in Patients With Head and Neck Cancer Undergoing Chemoradiation Therapy: A Post Hoc Analysis of 2 Randomized Trials

Mitochondrial Calcium Uniporter Regulates Metabolic Remodeling and Smooth Muscle Cell Proliferation in Type 2 Diabetes

Combined MR Volumetry and T2* Relaxometry Reveals the Olfactory System as an Iron-Dependent Structure Affected by Radiation

MIRO1 Is Required for Dynamic Increases in Mitochondria-ER Contact Sites and Mitochondrial ATP During the Cell Cycle

RetinaRegNet: A zero-shot approach for retinal image registration

Mouse model of radiation retinopathy reveals vascular and neuronal injury

Short‐Term Statin Treatment Reduces, and Long‐Term Statin Treatment Abolishes, Chronic Vascular Injury by Radiation Therapy

Changes in the Proteome of the Circle of Willis during Aging Reveal Signatures of Vascular Disease

Reduced blood flow by laser speckle flowgraphy after <sup>125</sup>I-plaque brachytherapy for uveal melanoma.

Cardiac Adverse Events Associated With Chemo‐Radiation Versus Chemotherapy for Resectable Stage III Non‐Small‐Cell Lung Cancer: A Surveillance, Epidemiology and End Results‐Medicare Study

Atrial-paced, exercise-similar heart rate envelope induces myocardial protection from ischaemic injury.

Mitochondrial Ca<sup>2+</sup> Uptake Drives Endothelial Injury By Radiation Therapy.

Mitochondrial Ca 2+ Uptake Drives Endothelial Injury By Radiation Therapy

Knockout of Sorbin And SH3 Domain Containing 2 (Sorbs2) in Cardiomyocytes Leads to Dilated Cardiomyopathy in Mice.

Knockout of Sorbin And SH3 Domain Containing 2 (Sorbs2) in Cardiomyocytes Leads to Dilated Cardiomyopathy in Mice

Sex-Specific Differences in Endothelial Function Are Driven by Divergent Mitochondrial Ca<sup>2+</sup> Handling.

Sex‐Specific Differences in Endothelial Function Are Driven by Divergent Mitochondrial Ca 2+ Handling

Longitudinal optical coherence tomography angiography (OCT-A) in a patient with radiation retinopathy following plaque brachytherapy for uveal melanoma.

Collaborators (13)

Bradley McDowell

Jui-Kai Wang

Ryan Boudreau

Barry London

Denice Hodgson-Zingman

John Buatti

Chad Grueter

Randy Kardon

Muhammad Imran

Daniel Hyer

Jared McLendon

Sakthivel Sadayappan

Mona Garvin

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