Daniela Ungureanu at University of Oulu - Research Interests, Publications & Academic Profile

Daniela Ungureanu

Associate Prof. (tenure)

University of Oulu

Finland

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Research Interests

Cell Biology

70%

Biochemistry

40%

Cancer Biology

50%

Cancer Therapy

30%

Receptor Biology

30%

Epithelial-mesenchymal Transition

30%

Ovarian Cancer

30%

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Recent Grants

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Regulatory mechanisms in ROR1 receptor pseudokinase signaling – from conformational switching to novel therapeutic targeting

Open Date: 2020-09-01

Close Date: 2024-08-01

Articles10

Drug response profiles in patient-derived cancer cells across histological subtypes of ovarian cancer

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Year:

2023

ROR1-STAT3 signaling contributes to ovarian cancer intra-tumor heterogeneity

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Year:

2023

Multiomics characterization implicates PTK7 in ovarian cancer EMT and cell plasticity and offers strategies for therapeutic intervention

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Year:

2022

High-throughput ex vivo drug testing identifies potential drugs and drug combinations for NRAS-positive malignant melanoma

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Year:

2022

New insights into the molecular mechanisms of ROR1, ROR2, and PTK7 signaling from the proteomics and pharmacological modulation of ROR1 interactome

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Year:

2022

Cellular thermal shift assay (CETSA) for determining the drug binding affinity using Ba/F3 clones stably expressing receptor pseudokinases.

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Year:

2022

Evaluating Targeted Therapies in Ovarian Cancer Metabolism

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Year:

2021

STRN-ALK rearranged pediatric malignant peritoneal mesothelioma – Functional testing of 527 cancer drugs in patient-derived cancer cells

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Year:

2021

Glucocorticoids induce differentiation and chemoresistance in ovarian cancer by promoting ROR1-mediated stemness

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Year:

2020

Structural Insights into Pseudokinase Domains of Receptor Tyrosine Kinases.

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Year:

2020

Collaborators11

Mariliina Arjama

University of Helsinki

FINLAND

Vilja Pietiäinen

University of Helsinki

FINLAND

Markku Varjosalo

University of Helsinki

FINLAND

Laura Kohtamäki

University of Helsinki

FINLAND

Heini Lassus

University of Helsinki

FINLAND

Brinton Seashore-Ludlow

Karolinska Institutet

SWEDEN

Tero Aittokallio

University of Helsinki

FINLAND

Aleksandr Ianevski

University of Helsinki

FINLAND

Astrid Murumägi

University of Helsinki

FINLAND

Sampsa Hautaniemi

University of Helsinki

FINLAND

Kari Salokas

University of Helsinki

FINLAND

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